Publications by authors named "Tandon S"

Background: Depression that occurs in pregnancy or postpartum (perinatal depression) impacts 1 in 5 mothers, yet access to effective and high-quality preventative interventions remains elusive for most. Digital interventions are a promising solution to this treatment gap because of the ubiquity of mobile devices and internet access. The Mothers and Babies Online Course (eMB) is an online adaptation of Mothers and Babies, an evidence-based preventative program for postpartum depression.

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Background: Lower calyceal anatomy makes the stone clearance a difficult task across all treatment formats. Improvement in optics and miniaturization of instruments have offered an effective and safer alternative to percutaneous nephrolithotomy (PCNL). The study was conducted to compare the efficacy and complications associated with mini-PCNL vs standard-PCNL.

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We discover strange nonchaotic attractor (SNA) through experiments in an unforced system comprising turbulent reactive flow. While models suggest SNAs are common in dynamical systems, experimental observations are primarily limited to systems with external forcing. We observe SNA prior to the emergence of periodic oscillations from chaotic fluctuations.

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Contrary to common chemical intuition, cation-π interactions can persist in polar, aqueous reaction solutions, rather than in dry non-coordinative solvent systems. This account highlights how alkali ion-π interactions impart distinctive structure-influencing supramolecular forces that can be exploited in the preparation of nanoscopic metal-organic capsules. The incorporation of alkali ions from polar solutions into molecular pockets promotes the assembly of otherwise inaccessible capsular entities whose structures are distinctive to those of common polyoxovanadate clusters in which {V=O} moieties usually point radially to the outside, shielding the molecular entities.

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  • - Human polyglutamine disorders are caused by abnormal expansions of CAG repeats in specific genes, leading to neurodegenerative diseases, but current therapies have been largely ineffective.
  • - This study explored a combination therapy using Drosophila models, targeting the insulin signaling pathway and identifying Drosophila Myc as a key partner that enhances rescue from poly(Q) induced neurodegeneration.
  • - The findings suggest that the collaboration between insulin receptor (InR) and Myc can alleviate various pathological issues of poly(Q) disorders, indicating their potential as a therapeutic strategy.
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Bacterial resistance to antibiotics and the number of patients infected by multi-drug-resistant bacteria have increased significantly over the past decade. This study follows a computational approach to identify potential antibacterial compounds from wild mushrooms. Twenty-six known compounds produced by wild mushrooms were docked to assess their affinity with drug targets of antibiotics such as penicillin-binding protein-1a (PBP1a), DNA gyrase, and isoleucyl-tRNA synthetase (ILERS).

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The flavor of vanilla is a complex blend of compounds, with vanillin as the most prominent, along with vanillyl alcohol and 4-hydroxybenzoic acid. Natural vanillin extracted from vanilla beans is expensive, so researchers use heterologous synthesis to produce nature-identical vanillin in plant hosts. Consequently, alternative traditional farming and gathering methods are required to bridge the significant disparity between supply and demand.

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  • The COVID-19 pandemic prompted researchers to adopt remote observational methods for studying parent-child interactions, particularly in socioeconomically and racially diverse families.
  • This study focused on remote assessments of 133 low-income parent-child dyads during a longitudinal study on postpartum depression interventions, adapting procedures for observing parenting and child behavior while ensuring reliability.
  • Findings indicated high participation satisfaction, with most families enjoying the remote assessments, and parents expressing a preference for virtual visits, highlighting the viability of remote research in diverse populations.
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  • Surgically treated pilonidal sinus disease (PSD) has high rates of wound complications, including surgical wound dehiscence, and this study aimed to see if negative pressure wound therapy (NPWT) can reduce these rates compared to conventional dressings.
  • A randomized controlled trial involved 50 patients aged 12-40 undergoing PSD excision, with equal splits between NPWT and conventional dressing; however, results showed no significant difference in wound dehiscence rates or recovery times between the two groups.
  • The study concluded that NPWT did not improve surgical outcomes for patients treated for PSD when compared to conventional passive dressings.
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Introduction: The incidence of recurrence of OKC varied from 2.5 to 62%. Studies have linked recurrence to treatment methods and also clinical and pathological features.

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A 44-year-old patient presented with hoarseness of voice and a polypoidal lesion on the left vocal cord. Complete excision was done. To our knowledge, this is the second reported case of molluscum contagiosum of the vocal cords.

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Unlabelled: Obstructive Sleep Apnea Hypopnea (OSAHS) Syndrome is defined by repetitive episodes of apneas or hypopneas, excessive daytime somnolence; waking up during sleep with gasping, choking, or breath holding; or witnessed reports of apneas, loud snoring, or both. The current gold standard diagnostic test for OSAS is polysomnography. A total of 30 patients diagnosed with stroke and OSA at tertiary care hospital were included in this study.

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Ergonomics in ENT Practice.

Indian J Otolaryngol Head Neck Surg

October 2024

The term Ergonomics is derived from two Greek words "Ergos" meaning work and "nomos" meaning laws. So, Ergonomics in simple term means "laws of work". It actually concerns with optimizing the relations between a worker and his work of environment.

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  • The study investigates the effectiveness of midazolam administrated orally vs. intranasally as preanesthetic medication for children aged 2-6 undergoing general anesthesia.
  • Results show both methods provide adequate sedation and minimal side effects, making them equally effective for easing children’s anxiety.
  • The findings suggest that while both routes are viable, the oral route is preferable for pediatric patients in dental procedures.
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Aim: To evaluate efficacy of oil pulling on caries activity of .

Materials And Methods: A randomized controlled experiment was designed, with 60 children chosen at random. Following that, the participants were divided into three groups-group A: oil pulling using cold pressed coconut oil (Perfora*); group B: commercially available fluoridated mouthwash (Kidodent*); group C: distilled water as control.

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The limited vanillin (3a) production from plant sources requires identifying some renewable and sustainable approaches for its synthesis. This study aimed to develop an efficient, eco-friendly process for synthesizing vanillin (3a) from eugenol (1a) and eugenol-rich essential oils. The chemical methodology for vanillin (3a) synthesis involved base-mediated isomerization of eugenol (1a) to isoeugenol (2a), followed by OsO/NaIO mediated oxidation of isoeugenol to vanillin (3a) using different additives such 1,4-diazabicyclo[2.

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Background: Immigrant Latinas (who are foreign-born but now reside in the USA) are at greater risk for developing postpartum depression than the general perinatal population, but many face barriers to treatment. To address these barriers, we adapted the Mothers and Babies Course-an evidence-based intervention for postpartum depression prevention-to a virtual group format. Additional adaptations are inclusion of tailored supplemental child health content and nutrition benefit assistance.

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Organophosphorus, an insecticide used in agricultural and industrial settings, is the most common cause of poisoning in India. Organophosphorus is a nerve poison that causes irreversible inhibition of acetylcholinesterase, which leads to the accumulation of acetylcholine, resulting in excessive cholinergic stimulation of several organ systems. Several complications have been reported, but pancreatitis is quite rare and mainly due to ductal hypertension and injury to parenchyma, consequent to cholinergic hyperactivity in the pancreas.

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Background: Peripheral neurectomy(PN)is a minimally invasive procedure, for the management of trigeminal neuralgi (TN)consisting of surgical avulsion of terminal branches of the trigeminal nerve.

Aim: To assess the efficacy of PN in the treatment of refractory TN and their recurrences in a follow up of 18 months.

Materials And Methodology: Retro-prospective and prospective study was conducted on randomly selected 30 TN patients irrespective of age, gender and socio-economic status.

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Article Synopsis
  • Neutrophil degranulation contributes to kidney damage in proliferative lupus nephritis (LN), suggesting it plays a role in the illness's progression.
  • Measuring specific neutrophil granule proteins in urine could help diagnose and monitor the severity of proliferative LN in patients.
  • The study found that urine levels of eight neutrophil granule proteins were significantly higher in patients with active LN compared to healthy individuals, and decreases in these proteins correlated with clinical remission.
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Aim: This case report aims to describe the management of a maxillary lateral incisor with a palatogingival groove (PGG) associated with a complex lesion.

Background: The PGG is a rare developmental anomaly that involves the lingual surface of the maxillary incisors and extends for varying distances and depths on the root surface. This anomaly is usually inconspicuous and funnel-shaped, which forms a niche where bacterial plaque and calculus can accumulate to levels significant for pathological changes resulting in endodontic and periodontal lesions.

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