[The effect of phospholipids on the adhesive properties of bacteria].

The present work shows that choline-containing phospholipids (lysophosphatidylcholine and lyso-1-alkyl-sn-glycerophosphocholine) inhibit the adhesion of some strains: Bacterium bifidum 1, B. adolescentis MC-42, B. longum B.

[Metabolic effect of lipostabil-forte].

Effects of lipostabil-forte containing unsaturated fatty acids on serum lipid concentrations, plasma and erythrocyte lipid and phospholipid fractions, immunoreactive insulin and thyroidal hormone levels were studied in 30 patients with coronary heart disease. During the therapy of all the patients within 1 month and occasionally 3 and 6 months, there was a statistically significant reduction in serum triglycerides, an increase in relative erythrocyte phospholipid levels and in plasma and erythrocyte phosphotylcholine, as well as reversal of hyperinsulinemia and improvement of thyroid function.

[Clinical role of lipid metabolism indices in the plasma and erythrocytes in progressive muscular dystrophies].

Patterns of lipid metabolism were studied in blood plasma and erythrocytes of patients with various forms of hereditary myopathies (Duchenn disease, Bekker-Kiner disease, Erba-Roth disease, Landuzy-Dejerin disease, Sharko-Mary neural amyotrophy). These diseases were characterized by a number of common patterns: deficiency of phospholipids, specific alterations in properties of lipoproteins and in content of cholesterol. In the Duchenn disease specific alterations typical for each step of the disease were shown.

[Evaluation of the effectiveness of hypolipidemic preparations in coronary arteriosclerosis].

Hypolipidemic therapy should be developed as a therapy aimed at the normalization of metabolism since the functional relationship of lipid and carbohydrate metabolism is evident both in normal and pathological conditions. The results of the reaction of the lipid spectrum of the blood to a single glucose load confirms that patients with combined hyperlipoproteinemias (IIb type) are heterogeneous in terms of the pathogenesis of the metabolic disturbances which should be taken into account in assessing the efficiency of hypolipidemic drugs as well as in selecting and administering medicines.

[Effect of hydrocortisone, adrenalectomy and their combination on the total lipid and phospholipid composition of the hepatocyte plasma membranes in rats].

A study was made of the effect of hydrocortisone and adrenalectomy on the content of lipids in plasma membranes of hepatocytes. Both long-term administration of hydrocortisone and adrenalectomy changed the content of total lipids and phospholipids of plasma membranes of liver cells.

[Clinico-biochemical parallels in neurotoxicoses in children].

The authors present the results of examining the plasma lipids in 62 children with an infectious neurotoxic syndrome. The children were suffering from acute respiratory viral infections, lobular pneumonia, or intestinal infections. Hyperlipidemia and dysphospholipidemia were revealed: the former was due primarily to a rise of the content of non-saturated fatty acids and triglycerides, and the latter to a drop of the lecithin and cephaline levels.

[Catecholamine levels in the striatum, hypothalamus, and adrenals of rats with genetic predisposition to epileptic seizures].

The content of catecholamines (CA) was studied in the basal ganglia, hypothalamus and adrenals of Krushinsky-Molodkina (KM) rats exhibiting the increased sensitivity to convulsants, and of non-audiogenic Wistar rats. It was found that in all the structures under test the content of CA was considerably higher in KM than in Wistar rats. At the same time the concentration of dopamine in the basal ganglia and hypothalamus was far greater than that of the subsequent reaction products (noradrenaline, homovanillic and dioxyphenyl acetic acids), and the concentration of dopamine in the adrenals exceeded that of noradrenaline and adrenaline.

[Clinico-biochemical correlates in adolescents with abnormal rates of psychophysical development].

The authors examined 106 adolescents with behaviour anomalies treated at Daytime Psychotherapeutic Ward of Moscow Children's Psychiatric Hospital No. 6. In 96 of them, borderline neuropsychic disturbances and in 10 schizophrenia were diagnosed.

[Changes in the cholesterol metabolism during electric stimulation of the skeletal muscles].

The effect of electric stimulation of the skeletal muscles on the content of cholesterol and atherogenic lipoproteins in blood serum, tissues, and bile was studied in experiments on rats subjected to long-term fixation and kept on an atherogenic diet. It is shown that electric stimulation of the muscles leads to a decrease in the content of cholesterol and atherogenic lipoproteins in blood serum and an increase in the tissue cholesterol content.