Experience and attitudes of pharmacists towards challenges and adaptive measures to new norm in ward pharmacy practice during the COVID-19 pandemic.

Background: COVID-19 pandemic has created challenges to the ward pharmacy practice. Challenges arose due to new norms in the ward pharmacy practice. Adaptive measures to overcome these challenges were important to sustain the quality of pharmaceutical care.

Adverse Events and Complications Associated With Vagal Nerve Stimulation: An Analysis of the Manufacturer And User Facility Device Experience Database.

Objective: Drug-resistant epilepsy (DRE) can have devastating consequences for patients and families. Vagal nerve stimulation (VNS) is used as a surgical adjunct for treating DRE not amenable to surgical resection. Although VNS is generally safe, it has its inherent complications.

Complete spinal cord injury from postoperative seroma following scoliosis surgery: A case report with favorable ambulatory outcomes after comprehensive rehabilitation.

Context: Postoperative seroma is a known complication following spine deformity surgery. However, complete spinal cord injury (SCI) due to postoperative seroma is rare. Rehabilitation strategies and outcomes of SCI associated with postoperative seroma have been inadequately described.

Use of botulinum neurotoxin in the treatment of piriformis syndrome: A systematic review.

Objective: To determine the pain, functional and adverse outcomes of patients with piriformis syndrome who received botulinum neurotoxin injection, and to determine the optimal dosing of botulinum neurotoxin and choices of modality used during this intervention.

Literature Survey: Systematic review of relevant clinical studies published in English language using PubMed/Medline, Embase and CINAHL databases from October 1, 2002 to October 6, 2020.

Methodology: A comprehensive search was performed to identify all studies addressing the treatment of piriformis syndrome with botulinum toxin.

Ultrasound-guided Genicular Nerve Blockade With Pharmacological Agents for Chronic Knee Osteoarthritis: A Systematic Review.

Background: Ultrasound-guided (ULSD-g) genicular nerve blocks (GNB) using pharmacological agents for pain control in chronic knee osteoarthritis (OA) are gaining in popularity. There lacks a systematic review to evaluate the ULSD techniques and pharmacological agents used during the intervention, and to assess the knee's function postintervention.

Objectives: Our study aimed to determine the clinical characteristics of patients with chronic knee OA selected for ULSD-g GNB, describe the various ULSD-g techniques and pharmacological agents used to target the genicular nerves, and evaluate the primary outcomes of pain and function.

Alcohol Motor Blocks: Case Series and a Narrative Review.

Alcohol neurolysis and intramuscular blocks are interventions for spasticity management. Here, we illustrate two clinical cases with spasticity impeding ease of care and pain which required selective alcohol intramuscular blocks with alcohol neurolysis. Post-interventions, both cases demonstrated improvement in pain and joint range of motion which facilitated better positioning and reduced caregiver burden.

Cervical neuromyelitis optica with thoracic ependymoma.

Background: The occurrence of cervical neuromyelitis optica (NMO) in a patient with a thoracic ependymoma is uncommon. Here, we present a patient with a spinal ependymoma who developed the new onset of NMO 2 months later.

Case Description: A 66-year-old male presented with right lower limb weakness.

Dextrose prolotherapy in knee osteoarthritis: A systematic review and meta-analysis.

Objective: To summarize the evidence for dextrose prolotherapy in knee osteoarthritis.

Data Sources: The authors searched PubMed and Embase from inception to September 2020. All publications in the English language were included without demographic limits.

Deep Learning for Interictal Epileptiform Spike Detection from scalp EEG frequency sub bands.

Epilepsy diagnosis through visual examination of interictal epileptiform discharges (IEDs) in scalp electroencephalogram (EEG) signals is a challenging problem. Deep learning methods can be an automated way to perform this task. In this work, we present a new approach based on convolutional neural network (CNN) to detect IEDs from EEGs automatically.

Botulinum Toxin Injection and Electromyography in Patients Receiving Anticoagulants: A Systematic Review.

Objective: To identify the different practice patterns of botulinum toxin injection (BTX) and electromyography (EMG) in patients receiving anticoagulation and to evaluate the incidence, reporting, and management of bleeding complications and compartment syndrome from BTX and EMG.

Literature Survey: Systematic review of relevant clinical studies in PubMed/Medline and Embase databases using key terms from inception to 31 May 2020. All publications in the English language were included without demographic limits.

A pilot project of early integrated traumatic brain injury rehabilitation in singapore.

Objective. Document acute neurosurgical and rehabilitation parameters of patients of all traumatic brain injury (TBI) severities and determine whether early screening along with very early integrated TBI rehabilitation changes functional outcomes. Methods.

Advances in rehabilitation medicine.

Rehabilitation medicine is the medical specialty that integrates rehabilitation as its core therapeutic modality in disability management. More than a billion people worldwide are disabled, and the World Health Organization has developed the International Classification of Functioning, Disability and Health as a framework through which disability is addressed. Herein, we explore paradigm shifts in neurorehabilitation, with a focus on restoration, and provide overviews on developments in neuropharmacology, rehabilitation robotics, virtual reality, constraint-induced therapy and brain stimulation.

Left ventricular fluid dynamics in heart failure: echocardiographic measurement and utilities of vortex formation time.

Background: In clinical heart failure (HF), inefficient propagation of blood through the left ventricle (LV) may result from suboptimal vortex formation (VF) ability of the LV during early diastole. We aim to (i) validate echocardiographic-derived vortex formation time (adapted) (VFTa) in control subjects and (ii) examine its utility in both systolic and diastolic HF.

Methods: Transthoracic echocardiography was performed in 32 normal subjects and in 130 patients who were hospitalized with HF [91, reduced ejection fraction (rEF) and 39, preserved ejection fraction (pEF)].

The impact of gender on the outcomes of invasive versus conservative management of patients with non-ST-segment elevation myocardial infarction.

Introduction: Studies have suggested that women who present with non-ST-segment elevation myocardial infarction (NSTEMI) may differ in their clinical response to early invasive strategy compared to male patients. We examined the impact of gender difference in NSTEMI patients on outcomes following invasive versus conservative treatment.

Materials And Methods: Patients enrolled in our national myocardial infarction (MI) registry between January 2000 and September 2005 with diagnosis of NSTEMI were retrospectively analysed.