Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings.

The RECOVERY study documented lower 28-day mortality with the use of dexamethasone in hospitalized patients on invasive mechanical ventilation or oxygen with COVID-19 Pneumonia. We aimed to examine the practice patterns of steroids use, and their impact on mortality and length of stay in ICU. We retrospectively examined records of all patients with confirmed Covid 19 pneumonia admitted to the ICU of Dubai hospital from January 1st, 2020 - June 30th, 2020.

C reactive protein elevation among children or among mothers' of children with autism during pregnancy, a review and meta-analysis.

Objective: To evaluate if children with ASD, or mothers of ASD children have elevated CRP during pregnancy.

Background: Autism spectrum disorder (ASD) is a neuro developmental disorder with incidence of 1 in 68 children occur in all racial, ethnic, and socioeconomic groups. Economic burden between $11.

Impact of Dobutamine in Patients With Septic Shock: A Meta-Regression Analysis.

Septic shock frequently requires vasopressor agents. Conflicting evidence exists for use of inotropes in patients with septic shock. Data from English studies on human adult septic shock patients were collected.

Using VistA electronic medical record data extracts to calculate the waiting time for total knee arthroplasty.

This is a retrospective database study of veterans who had total knee arthroplasty (TKA) at Veterans Affairs Connecticut Healthcare System. The objective of this study is to determine if VistA medical records data can be used to create a methodology for accurate assessment of waiting times for TKAs performed at Veterans Affairs facilities. The average waiting period from date of "initial consult" to date TKA was performed was greater than two years.

The Yale Guideline Recommendation Corpus: a representative sample of the knowledge content of guidelines.

Objective: To develop and characterize a large, representative sample of guideline recommendations that can be used to better understand how current recommendations are written and to test the adequacy of guideline models. We refer to this sample as the Yale Guideline Recommendation Corpus (YGRC).

Method: To develop the YGRC, we extracted recommendations from guidelines downloaded from the National Guideline Clearinghouse (NGC).

How often is strength of recommendation indicated in guidelines? Analysis of the Yale Guideline Recommendation Corpus.

Recommendation strength, is important for informed clinical decision making as it describes the authors judgment of benefits, risks, harms, and costs of adherence. We examined how often guideline authors documented strength by analyzing a representative sample of 1275 recommendations, the Yale Guideline Recommendation Corpus. We found variability and inconsistency in the way strength is reported.