[Cancer Notification by Hospital Doctors for Terminally-Ill Cancer Patients Referred to Visiting Physician].

Notification of cancer is essential for medical treatment based on patient preference. I studied 45 terminally-ill cancer patients referred to my clinic from January 2012 to December 2013. The data of each patient was retrospectively collected from their medical record.

Possible clinical cure of metastatic breast cancer: lessons from our 30-year experience with oligometastatic breast cancer patients and literature review.

Background: Metastatic breast cancer (MBC) is generally incurable. However, 10-20-year relapse-free survival of MBC is approximately 2%, implying that at least a small subset of MBC patients achieve prolonged survival. We therefore analyzed long-term outcome in a particular subset, i.

[Usefulness of epidural catheter with the subcutaneous reservoir for cancer pain control in homecare service].

The epidural block therapy is offered to reduce one of the side effects of systemic administration of opioids such as drowsiness. Hence, it is necessary to set a subcutaneous reservoir to prevent a catheter-related infection for a long period of time. One hundred twenty five patients with this manipulation during the year 2004 to 2010 showed a significant improvement in their pain level calculated by Numerical Rating Scale(NRS).

[Conditions required for home death--analysis of nine outpatients received chemotherapy].

Although a cancer patient to die at home has been arranged much easier due to a change in homecare service environment, the patient to die at home is not always possible. In the present study, we reviewed an outpatient who received chemotherapy and eventually died. We analyzed a relationship between the locations of their death and factors which influenced their final places using medical records.

[Questionnaire survey on patients receiving scheduled inpatient chemotherapy clarifies the issues of outpatient chemotherapy for advanced or recurrent colorectal cancer].

In recent 10 years, chemotherapy for advanced or recurrent colorectal cancer has progressed. FOLFOX and FOLFIRI regimens have been widely used for the patients with advanced colorectal cancer. Although these regimens can be administered without hospitalization via subcutaneous infusion reservoir, some patients prefer scheduled inpatient admissions for chemotherapy.

[A case report of delay in switching from inpatient treatment to home-based care due to changes in pain and other symptoms following chemotherapy].

The number of cancer patients and their families desiring home-based care has been increasing. A support system for home-based care is urgently needed for a patient who continues to receive cancer chemotherapy. We introduce a patient for whom the decision to switch from inpatient treatment to home-based care was delayed because of changes in various symptoms associated with chemotherapy.

[Current status and problems in the chemotherapy of our outpatient clinic in the department of clinical oncology].

The department of clinical oncology performed an analysis of the current situation and problems inherent to 4500 chemotherapies of the outpatient clinic for the last 20 months using a new department of the outpatient clinical treatment. Divided into primary organs and the application of chemotherapy are as follow: breast cancer 49%, and gastrointestinal cancer 47% (esophageal cancer 4%, stomach cancer 28%, colorectal cancer 15%) and others 4%. In terms of time consumed by chemotherapy, there were differences in the tumors, regimens and ages.

Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays.

The liver, skin, and gastrointestinal tract are major target organs of acute graft-versus-host disease (GVHD), the major complication of allogeneic bone marrow transplantation (BMT). In order to gain a better understanding of acute GVHD in the liver, we compared the gene expression profiles of livers after experimental allogeneic and syngeneic BMT using oligonucleotide microarray. At 35 days after allogeneic BMT when hepatic GVHD was histologically evident, genes related to cellular effectors and acute-phase proteins were up-regulated, whereas genes largely related to metabolism and endocrine function were down-regulated.