Publications by authors named "Tammy Y Chen"
Article Synopsis
- - Alphaviruses pose a threat to public health, and two monoclonal antibodies (mAbs), SKT05 and SKT20, show promise in providing protection against Venezuelan equine encephalitis virus (VEEV) in mouse models.
- - SKT20's effectiveness relies on Fc effector functions to prevent death from VEEV, while SKT05 can control viral spread and replication without these functions initially, but requires them later for full efficacy.
- - The study highlights how antibody avidity (strength of binding) is crucial for mAb effectiveness and suggests that understanding Fc-dependent mechanisms can help in developing better therapeutic treatments for alphavirus infections.
A Systematic Review of Adenomyosis: It Is Time to Reassess What We Thought We Knew about the Disease.
J Minim Invasive Gynecol
March 2021
Objective: To summarize and update our current knowledge regarding adenomyosis diagnosis, prevalence, and symptoms.
Data Sources: Systematic review of PubMed between January 1972 and April 2020. Search strategy included: "adenomyosis [MeSH Terms] AND (endometriosis[MeSH Term OR prevalence study [MeSH Terms] OR dysmenorrhea[text word] OR prevalence[Text Word] OR young adults [Text Word] OR adolesce* [Text Word] OR symptoms[Text Word] OR imaging diagnosis [Text Word] OR pathology[Text Word].