Ultrasound-assisted continuous flow synthesis of natural phenolic-coated FeO for magnetic solid phase extraction of tetracycline residues in honey.

Waste rubber bark abundant in phenolics can be used to produce an adsorbent for the enrichment and determination of tetracycline. FeO magnetic nanoparticles (FeO MNPs) coated with naturally extracted phenolics from waste rubber bark were synthesized for the first time by ultrasound combined with a continuous flow approach. The production of FeO MNPs with effective contact surface areas (45.

Synergy of iron-natural phenolic microparticles and hydrophobic ionic liquid for enrichment of tetracycline residues in honey prior to HPLC-UV detection.

Iron-natural phenolic microparticles were developed as absorbents for dispersive micro solid phase extraction (D-μSPE) synergistic with hydrophobic ionic liquid (IL) for dispersive liquid-liquid microextraction (DLLME) to enrich tetracycline residues, including tetracycline, doxycycline, oxytetracycline and chlortetracycline. In situ iron microparticles synthesized from betel nut natural reagent were employed as an adsorbent for D-μSPE. The hydrophobic IL [Hmim][PF] was synergistically utilized as an extraction solvent to extract and accumulate adsorbents bound with tetracyclines before quantitation by HPLC-UV.