Analysis of Metabolic Regulators PGC1-α and PGC1-β in Oral Squamous Cell Carcinoma with and without Hyperglycemia.

Aim: To assess the expression of PGC1-α and PGC1-β in Oral squamous cell carcinoma in the presence and absence of hyperglycemia.

Materials And Methods: Fresh tissue samples were collected from 14 well differentiated OSCC patients with hyperglycemia, 14 OSCC patients without hyperglycemia  and 14 healthy controls and subjected to quantitative real-time PCR to assess expression of PGC1-α and PGC1-β. The relative gene expression of PGC1-α and PGC1-β was calculated using the double delta Ct method.