Evaluation of Proanthocyanidin-based dentifrices on dentin-wear after erosion and dental abrasion - study.

Background: Proanthocyanidin has been considered as a preventive agent against erosion because of its properties, which involves remineralization, reduction of demineralization and matrix metalloproteinases (MMPs) inhibition. Thus, the aim of this in situ study was to evaluate the effect of proanthocyanidin-based dentifrices on wear resistance of dentin specimens subjected to erosion associated with abrasion.

Material And Methods: This crossover double-blinded study was performed in 5 phases of 5 days each, with 10 healthy volunteers who wore 5 palatal devices (1 for each phase) with 4 dentin specimens.

In situ effect of a proanthocyanidin mouthrinse on dentin subjected to erosion.

Background: Proanthocyanidin has been shown to be efficient in inhibiting matrix metalloproteinases.

Objective: The aim of this in situ study was to evaluate the protective effect of Proanthocyanidin-based mouthrinses either with naturally acidic or with a neutral pH applied on dentin subjected to erosion.

Methodology: Eight volunteers wore one palatal device in two phases (7 days washout) with 16 samples per group (n=8).