Publications by authors named "Tami S Gilderman"
High-grade serous ovarian carcinoma (HGSOC) is genetically unstable and characterised by the presence of subclones with distinct genotypes. Intratumoural heterogeneity is linked to recurrence, chemotherapy resistance, and poor prognosis. Here, we use spatial transcriptomics to identify HGSOC subclones and study their association with infiltrating cell populations.
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- The text discusses a cyanobacterial model organism crucial for studying its circadian clock, photosynthesis, and various biological processes.
- This organism is also significant for genetic engineering aimed at producing renewable biochemicals.
- The research highlights a SeAgo-based mechanism that defends against unwanted genetic material transfer and shows that deleting a specific gene can enhance genetic studies and engineering efforts.