Publications by authors named "Tamara Rothmeier"
Article Synopsis
- RNA binding proteins (RBPs) are essential for gene regulation by recognizing specific RNA targets, and various methods exist to study their binding preferences, like CLIP and SELEX.
- Current methods face challenges such as the need for purified proteins and extensive sequencing, which can limit their usage.
- The proposed RNA bind-n-seq method simplifies the process by using random RNA pools and allows for multiple selection rounds, improving motif identification without needing recombinant proteins.
Posttranscriptional processes in Bacteria include the association of small regulatory RNAs (sRNA) with a target mRNA. The sRNA/mRNA annealing process is often mediated by an RNA chaperone called Hfq. The functional role of bacterial and eukaryotic Lsm proteins is partially understood, whereas knowledge about archaeal Lsm proteins is scarce.
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