Publications by authors named "Tamara I Pajpanova"
Article Synopsis
- * Researchers used molecular modeling to design and analyze NT(8-13) analogs for binding to these receptors, confirming the importance of specific amino acid positions in receptor affinity.
- * The compound 10 showed better stability and ability to cross the blood-brain barrier, significantly improving motor function and memory in mouse models, indicating potential for new PD treatments.
The natural tridecapeptide neurotensin has been emerged as a promising therapeutic scaffold for the treatment of neurological diseases and cancer. In this work, we aimed to identify the top 100 most cited original research papers as well as recent key studies related to neurotensins. The Web of Science Core Collection database was searched and the retrieved research articles were analyzed by using the VOSviewer software.
View Article and Find Full Text PDFArginine residues are very important for the structure of proteins and their action. Arginine is essential for many natural processes because it has unique ionizable group under physiological conditions. Numerous mimetics of arginine were synthesized and their biological effects were evaluated, but the mechanisms of actions are still unknown.
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