Early Childhood Neurodevelopmental Outcomes in Infants Exposed to Infectious Syphilis In Utero.

Background: There are minimal neurodevelopmental follow-up data for infants exposed to syphilis in utero.

Methods: This is an inception cohort study of infants exposed to syphilis in utero. We reviewed women with reactive syphilis serology in pregnancy or at delivery in Edmonton (Canada), 2002 through 2010 and describe the neurodevelopmental outcomes of children with and without congenital syphilis.

Seroreversion of treponemal tests in infants meeting canadian surveillance criteria for confirmed early congenital syphilis.

Background: Few data exist on the serologic outcome of treponemal tests in congenital syphilis.

Methods: A chart review was conducted on all confirmed early congenital syphilis cases in Edmonton, Canada, from 2005-2010.

Results: Of the 16 cases identified, 11 (69%) infants seroreverted their treponemal tests by 18 months.