Publications by authors named "Tamara A Altieri"
Biochemistry
October 2013
Article Synopsis
- Human respiratory syncytial virus (hRSV) predominantly affects infants and the elderly, with the M2-1 protein playing a key role in viral processes like transcription and particle budding, making it a target for antiviral drugs.
- The M2-1 protein contains a zinc-binding motif crucial for its function; removing zinc turns it into a monomeric form while maintaining similar structural stability to its tetrameric state.
- This zinc removal process is potentially reversible and can be influenced by natural chelators, indicating that it may modulate M2-1's role in viral assembly and release.
