Publications by authors named "Tam D Pham"
Survivorship from congenital heart disease has improved rapidly secondary to advances in surgical and medical management. Because these patients are living longer, treatment and disease surveillance targets have shifted toward enhancing quality of life and functional status. Cardiopulmonary exercise testing is a valuable tool for assessing functional capacity, evaluating cardiac and pulmonary pathology, and providing guidance on prognosis and interventional recommendations.
View Article and Find Full Text PDFBidirectional ventricular tachycardia is a unique arrhythmia that can herald lethal arrhythmia syndromes. Using cases based on real patient stories, this article examines 3 different presentations to help clinicians learn the differential diagnosis associated with this condition. Each associated genetic disorder will be briefly discussed, and valuable tips for distinguishing them from each other will be provided.
View Article and Find Full Text PDFArticle Synopsis
- - TANGO2 deficiency disorder (TDD) is a rare genetic condition that leads to developmental delays, seizures, and serious metabolic and cardiac issues, and this study aimed to outline its natural history.
- - The research gathered data from 73 patients across 16 countries, revealing that most children show normal early development but experience a decline in milestones and various symptoms like ataxia and dystonia starting from ages 1 to 3.
- - Findings suggest that B-complex or multivitamin supplements can significantly reduce the occurrence of metabolic crises in these patients, offering a potential preventive measure.
Background: Data regarding recurrence risk among infants with supraventricular tachycardia (SVT) are limited.
Objectives: The purpose of this study was to determine incidence and factors associated with SVT recurrence.
Methods: This was a retrospective single-center study (1984-2020) with prospective phone follow-up of infants with structurally normal hearts diagnosed at age ≤1 year with re-entrant SVT.
Background: TANGO2 deficiency disorder (TDD) is an autosomal recessive disease associated with metabolic crisis, lethal cardiac arrhythmias, and cardiomyopathy. Data regarding treatment, management, and outcomes of cardiac manifestations of TDD are lacking.
Objective: The purpose of this study was to describe TDD-related cardiac crises.