Plasma levels of acylated and total ghrelin in pediatric patients with chronic kidney disease.

This cross-sectional study set out to compare total and acyl ghrelin levels in children with mild chronic kidney disease (CKD) undergoing conservative treatment (n = 19) with children with end-stage renal disease (ESRD) undergoing hemodialysis (n = 24), and with healthy controls (n = 20). The relationship between ghrelin levels and parameters of renal function, nutritional status, and selective hormones were investigated. ESRD patients had higher total ghrelin levels than those with mild CKD or control individuals.

Resting energy expenditure of children and adolescents undergoing hemodialysis.

Objective: We compared the resting energy expenditure (REE) of clinically stable children and adolescents on hemodialysis with that of healthy individuals, to investigate whether the current energy recommendations from the National Kidney Foundation/Kidney Disease Outcomes Initiative (NKF/DOQI) are adequate.

Patients And Methods: A cross-sectional study was conducted in 25 children and adolescents (15 male, SD 12.3 +/- 3.