Clinical findings and outcomes of eight dogs with surgically treated frontal sinus mucoceles.

Objective: To report clinical findings and outcomes of dogs surgically treated for frontal sinus mucocele.

Study Design: Short case series.

Animals: Eight dogs.

Case Report: Suspected Solitary Osseous Plasmacytoma in a Cat: Use of Magnetic Resonance Imaging to Diagnose and Confirm Resolution of Disease Following Chemotherapy.

A 9-year-old female spayed Domestic Shorthair cat presented for pain, reluctance to jump, and hyporexia of 14 days duration. Neurologic examination was consistent with C6-T2 myelopathy. Magnetic resonance imaging (MRI) revealed a solitary, contrast-enhancing lesion within the T2 vertebral body.

Alterations in amphetamine-stimulated dopamine overflow due to the Nurr1-null heterozygous genotype and postweaning isolation.

The nuclear receptor Nurr1 functions to regulate dopamine neurotransmission, as Nurr1-null heterozygous (+/-) mice have alterations in dopamine function and, when raised in isolation immediately after weaning, have disruptions in sensorimotor gaiting, a behavior altered in schizophrenia and modulated by dopamine neurotransmission. The goal of this study was to determine nigrostriatal and mesoaccumbens dopamine neurotransmission using microdialysis in +/- and wild-type (+/+) mice raised in groups or isolation. In the striatum, isolation significantly reduced amphetamine-stimulated dopamine overflow and levels of the dopamine metabolite 3,4-dihydroxyphenylacetic acid (DOPAC).