Publications by authors named "Talin Handa"
Background: Rhabdomyolysis is caused by muscle overuse, trauma, prolonged immobilization, drugs, or toxins. As rhabdomyolysis progresses, swelling and edema can compress surrounding structures. Few cases of the phenomenon occurring as a sequela of substance use have been described.
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- The study examines the impact of race on the presentation and outcomes of adults with Acromegaly (ACM) and Cushing's Disease (CD) caused by pituitary adenomas.
- Significant differences were noted in the clinical presentations, with Black patients more likely to present with headaches and a higher prevalence of diabetes in ACM, while also having more cases of hypopituitarism and macroadenomas in CD.
- Postoperative outcomes showed similar biochemical remission rates for ACM, but a borderline higher remission rate in White patients with CD, indicating possible disparities in diagnosis and treatment based on race.
Article Synopsis
- The study assessed how gender and the year of surgery influence the clinical presentation and outcomes in patients with acromegaly.
- The retrospective review included data from surgeries performed between 1994 and 2016, identifying significant differences in age, tumor size, and hormonal levels between male and female patients.
- Results showed comparable postoperative remission rates for both genders, but women experienced longer follow-up times and higher rates of normal IGF-1 levels, highlighting the need for tailored approaches to diagnosis and treatment based on these findings.