Publications by authors named "Talamini M"

Article Synopsis
  • Surgery generates extensive video data that is crucial for research, clinical outcomes, and education, but the entire data lifecycle requires standardized frameworks to ensure quality and compliance with ethical regulations.
  • Working groups comprised of clinicians and data experts collaborated to develop structured recommendations across key areas: Data Use, Structure, Exploration, and Governance using a modified Delphi process.
  • The consensus offers clear guidelines for standardized surgical video data management, emphasizing transparency, diversity, and attention to legal and ethical issues, aiming to improve data utilization for all stakeholders involved.
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Background: Solid pseudopapillary neoplasms (SPN) are rare tumors of the pancreas, typically affecting young women. Resection is the mainstay of treatment but is associated with significant morbidity and potential mortality. We explore the idea that small, localized SPN could be safely observed.

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Background: Surgical video recording provides the opportunity to acquire intraoperative data that can subsequently be used for a variety of quality improvement, research, and educational applications. Various recording devices are available for standard operating room camera systems. Some allow for collateral data acquisition including activities of the OR staff, kinematic measurements (motion of surgical instruments), and recording of the endoscopic video streams.

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Background: Improving perioperative efficiency helps reduce unnecessary surgical expenditure, increase operating room throughput, improve patient safety, and enhance staff and patient satisfaction. Lean Six Sigma (LSS) is a quality improvement model that has been successfully applied to eliminate inefficiencies in the business sector but has not yet been widely adopted in medicine. This study investigates the adaptation of LSS to improve operative efficiency for plastic surgery procedures.

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Background: The Global Evaluative Assessment of Robotic Skills (GEARS) rubric provides a measure of skill in robotic surgery. We hypothesize surgery performed by more experienced operators will be associated with higher GEARS scores.

Method: Patients undergoing sleeve gastrectomy from 2016 to 2020 were analyzed.

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Article Synopsis
  • The study evaluates the effectiveness of patient-derived organoids (PDOs) in predicting responses to neoadjuvant chemotherapy (NAT) in pancreatic adenocarcinoma patients.
  • Researchers created a biobank of 136 samples, achieving successful PDO generation from a diverse group of patients, and found that the PDO responses could reflect pathological responses to NAT, particularly with oxaliplatin.
  • The results highlight the feasibility of rapid PDO screening within a week of surgery, suggesting that these organoids could help personalize chemotherapy treatment for patients, improving initial treatment strategies.
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Background: Evaluation of robotic surgical skill has become increasingly important as robotic approaches to common surgeries become more widely utilized. However, evaluation of these currently lacks standardization. In this paper, we aimed to review the literature on robotic surgical skill evaluation.

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Background: Early postoperative weight loss can be predictive of one-year outcomes. It is unclear if poor performers identified in the first post-operative month can have improvement in outcomes with additional support and education.

Purpose: To evaluate the impact of a structured targeted support program for patients with lower-than-average early post-operative weight loss on 1-year outcomes.

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Background: Since 1997, the Fellowship Council (FC) has evolved into a robust organization responsible for the advanced training of nearly half of the US residency graduates entering general surgery practice. While FC fellowships are competitive (55% match rate) and offer outstanding educational experiences, funding is arguably vulnerable. This study aimed to investigate the current funding models of FC fellowships.

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Background: Although acute gastrointestinal injury (AGI) and feeding intolerance (FI) are known independent determinants of worse outcomes and high mortality in intensive care unit (ICU) patients, the incidence of AGI and FI in critically ill COVID-19 patients and their prognostic importance have not been thoroughly studied.

Methods: We reviewed 218 intubated patients at Stony Brook University Hospital and stratified them into three groups based on AGI severity, according to data collected in the first 10 days of ICU course. We used chi-square test to compare categorical variables such as age and sex and two-sample t-test or Mann-Whitney U-tests for continuous variables, including important laboratory values.

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Examine the possible beneficial effects of early, D-dimer driven anticoagulation in preventing thrombotic complications and improving the overall outcomes of COVID-19 intubated patients. To address COVID-19 hypercoagulability, we developed a clinical protocol to escalate anticoagulation based on serum D-dimer levels. We retrospectively reviewed all our first 240 intubated patients with COVID-19.

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Objective: The aim of this work is to formulate recommendations based on global expert consensus to guide the surgical community on the safe resumption of surgical and endoscopic activities.

Background: The COVID-19 pandemic has caused marked disruptions in the delivery of surgical care worldwide. A thoughtful, structured approach to resuming surgical services is necessary as the impact of COVID-19 becomes better controlled.

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Since the first appearance of the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) earlier this year, clinicians and researchers alike have been faced with dynamic, daily challenges of recognizing, understanding, and treating the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2. Those who are moderately to severely ill with COVID-19 are likely to develop acute hypoxemic respiratory failure and require administration of supplemental oxygen. Assessing the need to initiate or titrate oxygen therapy is largely dependent on evaluating the patient's existing blood oxygenation status, either by direct arterial blood sampling or by transcutaneous arterial oxygen saturation monitoring, also referred to as pulse oximetry.

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Introduction: Even though acute appendicitis is the most common general surgical condition encountered during pregnancy, the preferred approach to appendectomy in pregnant patients remains controversial. Current guidelines support laparoscopic appendectomy as the treatment of choice for pregnant women with appendicitis, regardless of trimester. However, recent published data suggests that the laparoscopic approach contributes to higher rates of fetal demise.

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Introduction: Current guidelines support laparoscopic cholecystectomy as the treatment of choice for pregnant women with symptomatic gallbladder disease, regardless of the trimester. Early intervention has remained the standard of care, but recent evidence has challenged this practice in pregnant women. We sought to compare surgical and maternal-fetal outcomes of antepartum versus postpartum cholecystectomy in New York State.

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Article Synopsis
  • Hospital readmissions after laparoscopic cholecystectomy (LC) are a significant cost and can strain the healthcare system, yet existing studies often underestimate their frequency due to limited scope.
  • A comprehensive analysis using the New York SPARCS database identified 591,627 adult patients undergoing LC from 2000 to 2016, revealing a 30-day readmission rate of 4.94%, with 4.58% being unplanned.
  • Factors influencing unplanned readmissions included age (patients over 65 or under 29), insurance type (Medicaid/Medicare patients), race, comorbidities, postoperative complications, and longer initial hospital stays.
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Introduction: The American Cancer Society recently lowered the recommended age for screening of colorectal cancer (CRC) to age 45 due to recent data showing increased incidence of CRC in younger populations. The purpose of this study was to evaluate if younger patients have increased likelihood of resection for CRC through the use of a statewide longitudinal database.

Methods: The New York SPARCS administrative database was used to identify all patients with diagnosis of colon cancer undergoing colorectal resections from 2000 to 2016.

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Article Synopsis
  • Bariatric surgery significantly reduces the risk of both microvascular and macrovascular complications in obese patients with type 2 diabetes compared to those managed medically.
  • A study analyzing patient records from 2006-2012 found that surgical patients had lower rates of complications, with a notable decrease observed over 1, 5, and 9 years.
  • The findings suggest that bariatric surgery could be an effective treatment option to improve long-term health outcomes for obese individuals suffering from diabetes.
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Article Synopsis
  • Utilization of robotic surgery for bariatric procedures has steadily increased from 6.7% in 2015 to 10.3% in 2018, with a total of 571,417 surgeries performed during the study period.
  • Clinical outcomes improved over time for both robotic and laparoscopic surgeries, with noticeable benefits for robotic surgeries in terms of reduced length of hospital stay and operative time.
  • In the 2018 analysis, laparoscopic Roux-en-Y gastric bypass was linked to more complications compared to robotic surgery, while laparoscopic sleeve gastrectomy showed less risk of specific postoperative issues.
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Background: Although bariatric surgery has been associated with a reduction in risk of obesity-related cancer, data on the effect of bariatric interventions on other cancers are limited.

Objectives: This study aimed to examine the relationship between bariatric interventions and the incidence of various cancers after bariatric surgery.

Setting: Administrative statewide database.

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Background: A novel coronavirus (COVID-19) erupted in the latter part of 2019. The virus, SARS-CoV-2 can cause a range of symptoms ranging from mild through fulminant respiratory failure. Approximately 25% of hospitalized patients require admission to the intensive care unit, with the majority of those requiring mechanical ventilation.

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Background: Surgeons are trained as "internists that also operate," bringing an important skillset to patient management during the current COVID-19 pandemic. A review was performed to illustrate the response of surgical staff during the pandemic with regard to patient care and residency training.

Methods: The evaluation and assessment of the changes enacted at Stony Brook Medicine's Department of Surgery is illustrated through the unique perspective of surgical residents.

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Article Synopsis
  • Small Bowel Obstruction (SBO) is a common reason for emergency department visits in the U.S., but there is limited information on patient outcomes after presentation.
  • A study using data from New York State's SPARCS database identified 43,567 ED visits for SBO from 2012 to 2014, revealing that most patients were admitted without surgery, while a smaller percentage underwent surgery.
  • The research indicates that while surgical patients had a higher risk of in-hospital death, they had lower rates of 30-day readmissions, with the overall rates of readmission, transfer, and death being relatively low.
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Introduction: Socioeconomic factors predispose certain populations to an increased exposure to emergent operative procedures. The aim of this study is to evaluate the role socioeconomic factors play in emergent repairs of inguinal, ventral and umbilical hernias.

Methods: The SPARCS database was used to identify all patients undergoing emergent ventral hernia repair (EVR), emergent inguinal hernia repair (EIR), and emergent umbilical hernia repair (EUR) between 2008 and 2015.

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