Exploring the Anti-tubercular Potential of 2-(1H-Pyrazol-1-yl) Pyrimidine: Design, Synthesis, Biological Evaluation and Molecular Docking Studies.

We designed and synthesized pyrazolyl pyrimidine containing derivatives and screened for anti-mycobacterial activity. Different spectral techniques like HRMS, 1H, and 13C NMR are deployed for the structural confirmation of the final derivatives. Final compounds were screened against the Mycobacterium tuberculosis (Mtb) H37Rv strain.