Publications by authors named "Talal Shaheer"
Article Synopsis
- Researchers developed pH-responsive polymeric hydrogels loaded with the antiviral drug favipiravir using free radical polymerization, optimizing the formulations through the Box-Behnken design method.
- The hydrogels showed high pH sensitivity and swelling capacity, with maximum swelling at pH 6.8 (2500%), a gel fraction of 97.8%, and an entrapment efficiency of up to 98%.
- In-vitro studies indicated that the hydrogels released between 85 to 110% of favipiravir within 24 hours, and the release kinetics primarily followed the Korsmeyer Peppas model, suggesting these hydrogels are effective for sustained drug delivery.
There is a long history of natural products for the treatment of infections and diseases. The objective of present study was to investigate the organoleptic, microscopic, physico-chemical, phytochemical, antidiarrheal and antidiabetic potential of leaf, flowering bud and stem bark of Moringa oleifera L. Macroscopic, microscopic, physico-chemical parameters and phytochemical screening were carried out.
View Article and Find Full Text PDFPeople prefer to use medicinal plants rather than chemical compounds because they are low cost and have fewer adverse events. Zingiber officinale Roscoe is a natural dietary rhizome with anti-oxidative, anti-inflammatory and anti-carcinogenic properties. Tribulus terrestris L.
View Article and Find Full Text PDFBackground: Cyclosporine A (CsA) is an exceptional immunosuppressant used for the treatment of immune disorders. Niosomal vesicles are promising drug carriers that are formed by self-association of nonionic surfactants and cholesterol in an aqueous phase. The objective of the study was to formulate combined nonionic surfactant based vesicles and to evaluate their in vitro characterization, release studies and in vivo studies.
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