Publications by authors named "Talal A Abd-ElRaheem"
The effect of H₁ and H₂ receptor antagonists on melanogenesis.
Indian J Dermatol Venereol Leprol
April 2016
Article Synopsis
- Histamine stimulates melanin production through H2 receptors in skin cells, leading to increased pigmentation after UVB exposure.
- Topically applied H2 antagonists effectively reduce this post-irradiation pigmentation, unlike H1 antagonists or placebo.
- The study highlights the mechanism by which H2 antagonists not only inhibit melanin production but also impair the transfer of melanin-containing organelles called melanosomes.