Publications by authors named "Tala Abdullah"
Article Synopsis
- - Landau-Kleffner syndrome (LKS) is a rare condition causing language regression and abnormal EEG patterns; early recognition and intervention are crucial for effective management.
- - A case study of an 8-year-old girl with language regression and suspected hearing loss revealed EEG abnormalities consistent with LKS, and treatment with speech therapy and valproic acid led to significant improvements.
- - The report emphasizes the need for a multidisciplinary approach involving various specialists to diagnose and manage LKS, and calls for more research to improve treatment and outcomes for affected children.
Article Synopsis
- - The study measured protein levels in 986 individuals to predict the severity of COVID-19, using both protein data and clinical risk factors to build predictive models.
- - A baseline model using age and sex achieved a prediction accuracy of 65%, but incorporating 92 specific proteins improved this accuracy to 88% in the initial group and maintained 86% in a separate test group.
- - Findings indicate that early-stage protein measurements can effectively predict COVID-19 severity, highlighting the need for further research to integrate these measurements into clinical practice.
Article Synopsis
- This study investigates how severe COVID-19 affects levels of immune-related proteins and their differences based on sex.
- Researchers analyzed data from 580 patients by measuring 147 immune proteins during the first 14 days of infection to uncover significant differences between severe cases and controls.
- The findings revealed that 69 proteins differed significantly between groups, and some proteins showed variations between sexes, which could help explain the differing outcomes in COVID-19 severity based on gender.
Background: Increased vitamin D levels, as reflected by 25-hydroxy vitamin D (25OHD) measurements, have been proposed to protect against COVID-19 based on in vitro, observational, and ecological studies. However, vitamin D levels are associated with many confounding variables, and thus associations described to date may not be causal. Vitamin D Mendelian randomization (MR) studies have provided results that are concordant with large-scale vitamin D randomized trials.
View Article and Find Full Text PDFTo identify circulating proteins influencing Coronavirus Disease 2019 (COVID-19) susceptibility and severity, we undertook a two-sample Mendelian randomization (MR) study, rapidly scanning hundreds of circulating proteins while reducing bias due to reverse causation and confounding. In up to 14,134 cases and 1.2 million controls, we found that an s.
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