Predictors and outcomes of same day discharge after minimally invasive hysterectomy in gynecologic oncology within the National Surgical Quality Improvement Program database.

Objective: To assess trends over time of same day discharge after minimally invasive hysterectomy in oncology, identify perioperative factors influencing same day discharge, and evaluate 30 day postoperative morbidity.

Methods: A retrospective cohort of elective minimally invasive hysterectomies performed for gynecologic oncologic indications between January 2013 and December 2021 was identified using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. Clinical and surgical characteristics, length of stay, and 30 day postoperative complications were captured.

Accuracy of Surgeon Self-Reflection on Hysterectomy Quality Metrics.

Objective: To evaluate the accuracy of gynecologic surgeons' self-reflection across hysterectomy case volume, proportion of cases performed using a minimally invasive approach (minimally invasive rate), and complication rate and to assess whether accuracy is associated with specific surgeon or practice characteristics.

Methods: This was a cross-sectional cohort study of gynecologic surgeons at eight Canadian hospitals between 2016 and 2019. Surgeons estimated case volume, minimally invasive rate, and complication rate for hysterectomies for a 6-month period using an online survey.

Navigating Tensions of Efficiency and Caring in Clerkship: A Qualitative Study.

Clerkship is a challenging transition during which medical students must learn to navigate the responsibilities of medical school and clinical medicine. We explored how clerks understand their roles as both medical learners and developing professionals and some of the tensionss that arise therein. Understanding how the clinical learning environment shapes the clerkship role can help educators foster compassionate care.

Clinical inertia in the pharmacological management of hypertension: A systematic review and meta-analysis.

Background: Clinical Inertia is defined as "failure of health care providers to initiate or intensify therapy according to current guidelines". This phenomenon is gaining increasing attention as a major cause of clinicians' failure to adequately manage hypertension, thus leading to an increased incidence of cardiovascular events. We performed a systematic review and meta-analysis of randomized controlled trials to determine whether interventions aimed at reducing clinical inertia in the pharmacological treatment of hypertension improve blood pressure (BP) control.

Synergy of cAMP and calcium signaling pathways in CFTR regulation.

Cystic fibrosis results from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel, leading to defective apical chloride transport. Patients also experience overactivation of inflammatory processes, including increased calcium signaling. Many investigations have described indirect effects of calcium signaling on CFTR or other calcium-activated chloride channels; here, we investigate the direct response of CFTR to calmodulin-mediated calcium signaling.