Publications by authors named "Tal Appel"

Article Synopsis
  • - The report compares hospitalized patients with COVID-19 (152 patients) and seasonal influenza (136 patients), noting distinct differences in disease severity and clinical symptoms.
  • - Influenza patients exhibited more issues like dyspnea, hypoxemia, and elevated liver enzymes, while COVID-19 patients were typically overweight, lymphopenic, and showed significant radiological abnormalities.
  • - Although influenza patients were generally more severely ill upon admission, both groups experienced comparable lengths of hospital stay, need for ventilatory support, and 30-day mortality rates.
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Objectives: To determine whether placental cell therapy PLacental eXpanded (PLX)-PAD (Pluristem Therapeutics, Haifa, Israel) may be beneficial to treating critically ill patients suffering from acute respiratory distress syndrome due to coronavirus disease 2019.

Design: Retrospective case report of critically ill coronavirus disease 2019 patients treated with PLacental eXpanded (PLX)-PAD from March 26, 2020, to April 4, 2020, with follow-up through May 2, 2020.

Setting: Four hospitals in Israel (Rambam Health Care Campus, Bnai Zion Medical Center, and Samson Assuta Ashdod University Hospital), and Holy Name Medical Center in New Jersey.

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