Publications by authors named "Takuya Takasawa"

Castration-resistant prostate cancer and multiple lymph node and ventral bladder metastases in an 87 year-old man progressed despite various systemic therapies, including chemotherapy. Because his prostate surgical specimen displayed a microsatellite instability (MSI) -high status, pembrolizumab 200 mg/body treatment was started. After six courses of treatment, his prostate-specific antigen (PSA) level decreased by 83% versus that at treatment initiation (from 408.

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Article Synopsis
  • A rare case of a germ cell tumor transformed into a malignant form was reported, specifically a testicular primitive neuroectodermal tumor with multiple metastases.
  • The patient, a 22-year-old man, underwent surgery, radiation, and chemotherapy after being diagnosed with a teratoma and initially responding to first-line treatment.
  • After experiencing a recurrence of skull metastasis, a successful second-line chemotherapy led to no disease progression three months later, highlighting the potential for effective multidisciplinary cancer treatment in such rare cases.
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