Publications by authors named "Takuto Torimitsu"

Article Synopsis
  • * In an experiment, genetically similar mice on a high-fat diet were either isolated or housed together for 12 weeks to study the effects on heart health and metabolism, using various biological analyses to measure changes.
  • * Findings revealed that socially isolated mice developed more severe atherosclerosis due to disrupted lipid metabolism and reduced oxytocin levels, suggesting that social connections enhance lipid management and overall cardiovascular health through a brain-liver communication pathway.
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Mineralocorticoid receptor (MR) and its ligand aldosterone play a central role in controlling blood pressure by promoting sodium reabsorption in the kidney. Coregulators are recruited to regulate the activation of steroid hormone receptors. In our previous study, we identified several new candidates for MR coregulators through liquid chromatography-tandem mass spectrometry analysis using a biochemical approach.

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Alström syndrome (AS) is an extremely rare disease accompanied by blindness, hearing loss, obesity, type 2 diabetes, dilated cardiomyopathy, and progressive hepatic and renal dysfunction. The life span of AS patients rarely exceeds 50 years, and thus there are very few reports describing the implementation of renal replacement therapy for these patients. We here report a case of AS patient who exhibited dilated cardiomyopathy, end-stage renal disease, and hepatic cirrhosis.

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Thromboembolism is one of the most serious complications of nephrotic syndrome (NS). Although the occurrence of renal vein thrombosis or deep vein thrombosis is well recognized in NS patients, they rarely develop cerebral venous thrombosis (CVT). The mortality rate of CVT patients is still approximately 10%, and 6-10% of patients who survive have a severe and permanent disability.

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