Publications by authors named "Takuto Okada"
Article Synopsis
- Cystic fibrosis (CF) is caused by mutations in the CFTR gene and is more common in Caucasians than in East Asians; this study investigated CF characteristics in Japanese patients.
- The analysis of 132 CF patients revealed prevalent symptoms such as chronic lung disease (85.6%) and pancreatic insufficiency (66.7%), with a median survival age of just 25 years.
- The study found distinct CFTR variant patterns in Japanese patients compared to European ones, with specific variants like CFTR-dele16-17a-17b being more common in Japan and the F508del variant appearing in European alleles.
