Publications by authors named "Takuro Akashi"
Background: Coughing and other distress during bronchoscopy are undesirable for both patients and bronchoscopists. The efficacy of local anesthetics administered via aerosol sprays in the airways has been documented; however, the optimal administration method remains unclear. Furthermore, the efficacy of continuous salivary aspiration in reducing cough and other distress has not yet been evaluated.
View Article and Find Full Text PDFThyroid transcription factor 1 (TTF-1) is primarily expressed in lung and thyroid cancers, but it has also been observed in other cancers. A 60-year-old woman presented with worsening dyspnea, pleural effusion, lung metastases, a right ovarian tumor, and para-aortic intra-abdominal lymph node metastasis. Biopsies from the pleural dissemination revealed TTF-1-positive adenocarcinomas.
View Article and Find Full Text PDFArticle Synopsis
- A 60-year-old woman was diagnosed with advanced lung cancer (stage IVB) with a specific genetic mutation and began treatment with osimertinib.
- After one month of osimertinib treatment, she developed cough and lung issues due to drug-induced pneumonitis, which resolved after stopping the medication.
- Twenty months later, she had brain and leptomeningeal metastases; osimertinib was restarted successfully without causing pneumonitis for another eight months.