Publications by authors named "Takuma Iwasaki"

Article Synopsis
  • - The study explores how different-sized protein aggregates affect the performance of virus removal filters by creating fouling, or blockage, in the filtration process.
  • - Human immunoglobulin G was heated to form protein aggregates of various sizes, which were then filtered through the Planova 20N membrane, revealing that larger aggregates tend to collect closer to the membrane surface while smaller ones penetrate deeper.
  • - The findings highlight the membrane's gradient structure, which helps minimize fouling by preventing larger aggregates from clogging smaller pores, and they suggest that the clogging behavior evolves from complete blockage to cake filtration over time.
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Bongkrekic acid (BKA) inhibits adenine nucleotide translocator (ANT) and suppresses ADP/ATP exchange in the mitochondrial inner membrane. Previously, we demonstrated that BKA exhibited cytotoxic effects on 4T1 tumor cells, depending on the cell number in the culture, but not on NIH3T3 cells. However, the cause of this differential sensitivity was unelucidated.

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Tailed bacteriophages (Caudovirales) are divided into three families: Myoviridae with long contractile tails, Siphoviridae with long noncontractile tails and Podoviridae with short noncontractile tails. All have an icosahedral head with a portal vertex connected to a neck structure followed by a tail. Bacteriophage Mu belongs to the Myoviridae family.

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