Long-term follow-up of a single dose of fluralaner in nine dogs with demodicosis.

Background: Long-term follow-up of oral fluralaner for canine demodicosis has not been demonstrated.

Objectives: A multicentre prospective open trial for the efficacy of oral fluralaner for the long-term (>12 month) management of canine demodicosis.

Animals: Client-owned dogs diagnosed with demodicosis at nine veterinary clinics.

Characterization of a variant CD4 molecule in Japanese Black cattle.

Monoclonal antibodies (mAbs) that recognize cluster of differentiation (CD) molecules on lymphocytes are useful tools for the study of different lymphocyte subsets in flow cytometry (FCM) analysis. CD4 is a glycoprotein found on the surfaces of helper T cells, monocytes, macrophages, and dendritic cells. In this study, we describe Japanese Black (JB) calves in a farm whose peripheral blood mononuclear cells (PBMCs) did not react with a CD4-specific mAb.

Change in the responsiveness of interferon-stimulated genes during early pregnancy in cows with Borna virus-1 infection.

Background: Borna disease virus is a neurotropic pathogen and infects the central nervous system. This virus infected a variety of animal species including cows. The most of cows infected with Borna disease virus 1 (BoDV-1) exhibit subclinical infection without any neurological symptoms throughout their lifetime.