Publications by authors named "Taku Ikegami"
Case: A 62-year-old woman receiving romosozumab for 3 months underwent extreme lateral interbody fusion (XLIF) for lumbar degenerative spondylolisthesis. From 1 week after surgery, she experienced gradually increasing pain from the right groin to the front of the thigh. Examination revealed ossifying myositis in bilateral psoas major muscles.
View Article and Find Full Text PDFArticle Synopsis
- Trans-sacral canal plasty (TSCP) is a minimally invasive lumbar spine surgery performed under local anaesthesia, suitable for patients with or without prior spine surgeries.
- The study analyzed data from 112 patients who underwent TSCP, finding that 30.4% required open revision surgery after the procedure during a follow-up of 7-23 months.
- Key risk factors for needing open revision surgery included intervertebral instability and a narrow dural sac area, indicating the importance of these conditions when considering TSCP.
IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria.
Proc Natl Acad Sci U S A
February 2024
Invariant natural killer T (iNKT) cells are innate-like T lymphocytes that express an invariant T cell receptor α chain and contribute to bridging innate and acquired immunity with rapid production of large amounts of cytokines after stimulation. Among effecter subsets of iNKT cells, follicular helper NKT (NKT) cells are specialized to help B cells. However, the mechanisms of NKT cell differentiation remain to be elucidated.
View Article and Find Full Text PDFCase: A 58-year-old man presented with lumbar spinal stenosis due to epidural lipomatosis. He underwent transsacral canal plasty (TSCP), in a manner similar to epidural adhesiolysis, which can be performed under local anesthesia. His leg pain improved dramatically in the year after surgery.
View Article and Find Full Text PDFCase: A 73-year-old woman presented with degenerative kyphoscoliosis. Radiographs revealed sagittal and coronal imbalance with lumbar spinal stenosis. Extreme lateral interbody fusion (XLIF) was performed in the first stage of 2-stage surgery, and a closed-suction drainage tube was placed in the retroperitoneal cavity.
View Article and Find Full Text PDFBackground: Surgical treatment of spinal metastases has been associated with high morbidity and mortality in patients with sarcopenia based on low skeletal muscle mass. We assessed physical performance using the Eastern Cooperative Oncology Group performance status scale and the Barthel Index on the 30th day after palliative surgery for spinal metastases and investigated the effectiveness of surgery according to sarcopenia assessed by skeletal muscle mass.
Methods: We retrospectively analyzed 78 consecutive patients with thoracic and lumbar spinal metastases who underwent palliative surgery.