Publications by authors named "Tako Djimefo Alex Kevin"

Background: The spread of drug resistance is a significant issue, particularly in endemic countries with limited resources. The aim of this study was to evaluate antimalarial and antioxidant activity of in order to justify its use in traditional medicine.

Methods: Evaluation of the antimalarial activity of was carried out according to the model of the suppressive and curative test of Peters' over 4 days in infected mice.

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Geohelminthiases are endemic in Chad and constitute a serious public health problem. This study aimed at determing the prevalence and risk factors of intestinal geohelminthiasis in children aged 5-15 years in the city of Moundou, Chad. This was a cross-sectional and descriptive study carried out in the city of Moundou.

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Background: Cerebral malaria is one of the most severe and dangerous forms of malaria and is potentially fatal. This study was aimed at evaluating the anticerebral malaria efficacy of used by traditional healers.

Method: Fifty grams of stem bark was macerated in 1 L ethanol (95%) for 72 h.

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Background: Malaria remains a major public health problem in the tropical and subtropical regions. This study aimed of investigating the antimalarial and antioxidant activities of ethanol extract of stem bark. .

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Background: Schistosomiasis is endemic in Cameroon and continues to cause serious public health problems, especially among populations in rural areas. This study aimed at determining the prevalence and risk factors of urinary and intestinal schistosomiasis in Manjo.

Method: A cross-sectional study was conducted in the city of Manjo in 2020.

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Background: Reduction of oxidative stress during malaria infection is considered as being of great benefit so long as treatment and drug development approaches are concerned. This study had the aim of evaluating the antimalarial and antioxidant activities of the ethanolic extract of in Swiss albino mice infected with the NK65 strain.

Methods: the antiplasmodial activity of the plant ethanolic extract was tested in a four-day suppressive and curative assay using in Swiss albino mice.

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Introduction: Resistance to common antimalarial drugs and persistence of the endemicity of malaria constitute a major public health problem in Cameroon. The aim of this study was to evaluate the antiplasmodial, antioxidant, and cytotoxic activities of aqueous and ethanol extracts of used by Cameroonian traditional healers for the treatment of malaria.

Methods: Aqueous and ethanolic stem bark extracts were prepared according to standard procedures.

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Background: Malaria is a serious public health problem, especially in sub-Saharan Africa. The aim of this study was to scientifically provide baseline information on the use of stem bark as an antimalaria drug by traditional healers.

Method: The stem barks of were harvested and dried to obtain powder, and fifty grams of the powder were soaked in ethanol and hot distilled water respectively, for the preparation of ethanol and aqueous extracts, then dried in an oven at 40°C for the ethanol extract and 50°C for the aqueous extract.

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Background: Malaria is the leading cause of morbidity and mortality in African countries. We aimed this study at evaluating the antiplasmodial, antioxidant, and cytotoxicity activity of extracts.

Method: The aqueous and ethanol extracts were obtained by maceration.

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