Publications by authors named "Takeyuki Sambe"
Article Synopsis
- This study examined the effectiveness of cardiac rehabilitation (CR) on patients recovering from ST-segment elevation myocardial infarction (STEMI) treated with modern medical interventions.
- Among the 145 patients reviewed, those who completed an outpatient CR program showed better outcomes, with an 88% survival rate free of major adverse cardiac and cerebrovascular events (MACCE) compared to 76% in those who did not participate in CR.
- The findings suggest that participating in CR may significantly improve mid-term prognosis and overall health in STEMI patients, with noticeable enhancements in physical fitness metrics post-rehabilitation.
Article Synopsis
- Hepcidin-25 is a crucial peptide for managing iron levels in the body and inflammation, and this study explores its potential harmful effects on atherosclerosis and coronary plaque vulnerability.
- The study measured serum hepcidin-25 levels in patients with acute myocardial infarction (MI) and stable angina, finding higher levels of hepcidin-25 and inflammatory markers in acute MI patients, along with evidence of hepcidin-25 present in coronary plaque macrophages.
- Findings suggest that increased hepcidin-25 contributes to plaque instability by causing endothelial cell death, highlighting its role in the pathophysiology of coronary artery diseases.