Publications by authors named "Takeshi Nojo"

The objective of this study was to investigate the incremental prognostic value for adverse events of myocardial blood flow (MBF) derived from stress computed tomography perfusion (CTP) at remote myocardium over cardiac risk factors and ischemia. We prospectively analyzed 242 patients who underwent dynamic CTP and CT angiography. Adverse events were defined as a composite of all-cause mortality, non-fatal myocardial infarction, unstable angina, heart failure requiring hospitalization, peripheral artery disease, and stroke.

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Objectives: To compare the incidence rate of reintervention in patients with and without complication findings at aortic computed tomography using double region of interest timing bolus (DRTB) method after endovascular stent placement of the aorta.

Methods: We included 40 patients who underwent computed tomography of the aorta using DRTB method after endovascular stent placement. DRTB method allows to scan the aorta with a short injection time of 9 s by synchronizing the scan speed to the aortic flow.

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To investigate the feasibility of aortic computed tomography angiography (CTA) performed at 80 kVp in lean patients using the double region of interest timing bolus (DRTB) technique compared to 100 kVp scanning. This study was approved by the institutional ethics committee, and all patients provided written informed consent. We prospectively included 165 patients from July 2018 to February 2019.

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The purpose of this study was to investigate the feasibility of a double ROI timing bolus technique for performing aortic CT angiography (CTA) with 40 mL of contrast medium over 9 seconds. A prospective study from February to July 2018 included 106 patients with clinical indications for evaluation of aortic aneurysm or dissection or suspected aortic disease. Forty-seven of these patients had undergone prior aortic CTA by the conventional method.

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This article describes data related to a research article titled "Feasibility of dynamic myocardial CT perfusion using single-source 64-row CT", Tomizawa et al. (in press) [1]. Decrease in the myocardial blood flow could be calculated by performing stress dynamic computed tomography perfusion.

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Background: Dynamic myocardial computed tomography perfusion (CTP) is an emerging technique to diagnose significant coronary stenosis. However, this procedure has not been reported using single-source 64-row CT.

Objective: To investigate the radiation dose and the diagnostic performance of dynamic CTP to diagnose significant stenosis by catheter exam.

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Aims: To investigate the relationship of type 2 diabetes duration and myocardial blood flow (MBF) assessed by myocardial CT perfusion.

Materials And Methods: We prospectively included 140 patients with type 2 diabetes who underwent dynamic myocardial CT perfusion exam. MBF of the remote myocardium was calculated using the deconvolution technique and the Voronoi method.

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Objective: To compare the diagnostic performance of estimated energy loss (EEL) with diameter stenosis (DS) to estimate significant stenosis by fractional flow reserve (FFR).

Materials And Methods: One hundred twenty-five patients were included. EEL was calculated using DS, lesion length, minimal lumen area and left ventricular volume.

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Rationale And Objectives: The purpose of this study was to investigate whether high-risk plaque (HRP) and calcium assessed by coronary computed tomography (CT) could predict future cardiovascular events after second-generation drug-eluting stent (DES) placement.

Materials And Methods: We analyzed 317 patients from December 2012 to April 2015 who underwent coronary CT followed by DES placement. HRP was defined as a plaque with positive remodeling and low attenuation or a plaque with a napkin-ring sign.

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Although molecular positron emission tomography imaging of amyloid and tau proteins can facilitate the detection of preclinical Alzheimer's disease (AD) pathology, it is not useful in clinical practice. More practical surrogate markers for preclinical AD would provide valuable tools. Thus, we sought to validate the utility of conventional magnetic resonance spectroscopy (MRS) as a screening method for preclinical AD.

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Purpose: To survey whether imaging is being performed appropriately in Japan, and to survey whether radiologists intervene to ensure imaging requests are appropriate.

Methods: An online survey was sent to radiologists at accredited radiology training hospitals. The survey included the radiologists' perspectives on whether imaging is performed appropriately at their institutions and whether they intervene if the indication for imaging is inappropriate/ambiguous.

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Background: Thin-cap fibroatheroma (TCFA) is assumed to cause acute coronary syndromes.

Objective: To compare the accuracy of different models for diagnosing TCFA using parameters derived by CT, validated against optical coherence tomography (OCT).

Methods: One hundred twenty-nine plaques in 106 patients were analyzed using data acquired by 64-row CT with a reconstruction thickness of 0.

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Objectives: Current clinical models predict the pre-test probability of obstructive coronary artery disease, but these models do not predict the presence of high-risk plaques. Thus the objective of this study was to propose a model to predict high-risk plaque assessed by coronary computed tomography (CT) angiography.

Methods: This study was a retrospective cross-sectional study.

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The objective of this study was to investigate the relationship between the severity of hepatic steatosis and coronary artery disease characteristics assessed by coronary computed tomography (CT) angiography. This retrospective analysis consisted of 2028 patients. Hepatic steatosis was evaluated by liver attenuation on unenhanced CT and the patients were divided into four groups (≥60 HU, 54-59 HU, 43-53 HU, ≤42 HU).

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Background: Coronary artery aneurysm (CAA) is occasionally detected on a small percentage of coronary angiography or multi-detector computed tomography (MDCT). CAA itself is considered benign entity despite the potential risks of rupture, thromboembolism, and compression of surrounding structures. However, the optimal management including other vascular comorbidity has yet to be fully clarified.

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The objective of this study was to investigate the relationship of Hemoglobin A1c (HbA1c) and plaque characteristics including high risk plaque and plaque extent. We retrospectively examined 1079 consecutive coronary computed tomography (CT) angiography scans and the HbA1c results. We divided the patients into four groups by the HbA1c status: non-diabetic, ≤6.

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Purpose: To clarify the workload of certified radiologists and to estimate the current manpower shortages in Japan.

Methods: We conducted a questionnaire survey for accredited training institutions. The contents included the radiologist employment pattern (full vs.

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The purpose of this study was to investigate the difference of coronary artery disease (CAD) severity and extent as well as plaque characteristics between patients with either one of hypertension (HT), diabetes mellitus (DM) or dyslipidemia (DL). We retrospectively reviewed the records of 1,161 patients (HT 442, DM 77, DL 248, no disease 394) who underwent coronary computed tomography angiography. Stenosis severity was classified as normal, non-obstructive (1-49 % stenosis), moderate (50-69 % stenosis) or severe (≥70 % stenosis).

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Article Synopsis
  • This study aimed to evaluate how well coronary computed tomography angiography (CTA) diagnoses coronary artery conditions, especially when dealing with unclear segments that could be either obstructive or non-obstructive.
  • Researchers analyzed data from 268 patients and found that treating unclear segments as non-obstructive significantly improved the diagnostic performance of CTA, boosted by the introduction of a measurement called contrast medium arrival time adjusted by heart rate (CATHR).
  • The findings indicated that using CATHR not only increased the accuracy of CTA results but also enhanced its ability to correctly identify true positives and negatives, establishing it as a valuable factor for improving diagnostic accuracy.
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Background: Several methods have been developed to reduce the radiation dose in coronary computed tomography angiography (CTA).

Objective: The objective of our study was to evaluate the effects of Adaptive Iterative Dose Reduction (AIDR) on objective and subjective image quality as well as the radiation dose, compared with conventional filtered back projection (FBP), in coronary CTA.

Methods: We retrospectively reviewed 100 consecutive patients who underwent coronary CTA.

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The purpose was to investigate the influence of shorter delay time on the interpatient variability in coronary enhancement and appropriateness of scan timing in coronary CT angiography (CTA) using bolus tracking method with 320-row CT. The bolus tracking scan was performed at the level of the bifurcation of the trachea for first 50 patients (group 1) and at the center level of the diagnostic scan for the last 50 patients (group 2). The CT number of the proximal coronary arteries was measured in the right coronary artery (RCA) and the left main trunk (LMT).

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Objective: The purpose of this study was to evaluate the correlation between bolus-tracking parameters and heart rate (HR) with attenuation of the ascending aorta and create a linear regression model for predicting coronary attenuation in coronary computed tomography angiography (CCTA).

Methods: A total of 50 patients (31 men, 19 women; mean age, 67.2±10.

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Purpose: To perform a systematic review of the literature regarding the use of a saline chaser in abdominal computed tomography (CT).

Materials And Methods: The MEDLINE database was searched from 1966 to March 2007. Studies were included if they compared the magnitude of contrast enhancement with and without a saline chaser in CT and reported CT contrast enhancement values of the liver, portal vein, or abdominal aorta.

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Purpose: True pancreaticoduodenal artery aneurysms are rare. No definitive study evaluating the natural history of these lesions or their preferred method of treatment has been published. The purpose of this study was to evaluate the outcome of preventive treatment of unruptured pancreaticoduodenal artery aneurysms using a Markov model.

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