Estimation of radioactivity in single-photon emission computed tomography for sentinel lymph node biopsy in a torso phantom study.

Objective: The number of lymph nodes to be removed is determined from residual counts. Advance estimation of residual radioactivity in lymphatic nodes before a biopsy is useful for reducing surgical operation time. The purpose of this study was to estimate the total radioactivity of a small hotspot in single-photon emission computed tomography (SPECT) of a torso phantom.

Detection of lung cancer by FDG-PET cancer screening program: a nationwide Japanese survey.

Aim: The aim of this study was to analyze the lung cancer detection rate in asymptomatic individuals by the Fluorine-18 fluorodeoxyglucose-positron emission tomography FDG-PET cancer screening program in Japan.

Materials And Methods: A total of 153,775 asymptomatic individuals underwent the FDG-PET cancer screening program; the 854 cases with findings that indicated suspected lung cancer by any detection method were analyzed.

Results: Among the 854 cases, 319 were verified as lung cancer.

The current status of an FDG-PET cancer screening program in Japan, based on a 4-year (2006-2009) nationwide survey.

Objective: The aim of this study was to survey the 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) cancer screening program conducted in Japan.

Methods: The "FDG-PET cancer screening program" included both FDG-PET and positron emission tomography with computed tomography (PET/CT) with or without other combined screening tests that were performed for cancer screening in asymptomatic subjects. A total of 155,456 subjects who underwent the FDG-PET cancer screening program during 2006-2009 were analyzed.

Comparative study of the value of dual tracer PET/CT in evaluating breast cancer.

The present study was conducted to assess the relationship between tumor uptake and pathologic findings using dual-tracer PET/computed tomography (CT) in patients with breast cancer. Seventy-four patients with breast cancer (mean age 54 years) who underwent (11)C-choline and 2-[(18)F]fluoro-2-deoxy-d-glucose ((18)F-FDG) PET/CT prior to surgery on the same day were enrolled in the present study. Images were reviewed by a board-certified radiologist and two nuclear medicine specialists who were unaware of any clinical information and a consensus was reached.

[Optimization of the scan time is based on the physical index in FDG-PET/CT].

Purpose: The image quality of Positron Emission Tomography (PET) using (18)F-fluoro-2-deoxy-D-glucose is extremely important to diagnose cancer precisely. The purpose of this study is to inspect the physical indexes that are correlated with image quality and optimization of the scan time, utilizing the physical index.

Methods: This study calculated two kinds of patient noise equivalent counts (NEC(patient) and NEC(density)) and signal to noise ratio in liver (SNR(liver)) to measure PET image quality.

Radiation exposure and risk-benefit analysis in cancer screening using FDG-PET: results of a Japanese nationwide survey.

Objective: The aim of this study was to estimate radiation exposure and evaluate the risks and benefits of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in cancer screening.

Methods: A nationwide survey of FDG-PET cancer screening was conducted in 2006, and the results were analyzed with a common index, "extension/shortening of the average life expectancy."

Results: The average estimated effective dose was 4.

Analysis of various malignant neoplasms detected by FDG-PET cancer screening program: based on a Japanese Nationwide Survey.

Objective: The most distinctive feature of FDG-PET cancer screening program is the ability to find various kinds of malignant neoplasms in a single test. The aim of this survey is to clarify the range and frequency of various malignant neoplasms detected by FDG-PET cancer screening performed in Japan.

Methods: "FDG-PET cancer screening" was defined as FDG-PET or positron emission tomography and computed tomography (PET/CT) scan with or without other tests performed for cancer screening of healthy subjects.

A meta-analysis of (18)F-Fluoride positron emission tomography for assessment of metastatic bone tumor.

Purpose: The aim of this study was to assess the diagnostic performance of (18)F-Fluoride positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) compared with bone scintigraphy (BS) planar or BS planar and single photon emission computed tomography (SPECT) in evaluating patients with metastatic bone tumor.

Materials And Methods: We performed a meta-analysis of all available studies addressing the diagnostic accuracy of (18)F-Fluoride PET, (18)F-Fluoride PET/CT, BS planar, and BS planar and SPECT for detecting the metastatic bone tumor. We determined sensitivities and specificities across studies, calculated positive and negative likelihood ratios, and drew summary receiver operating characteristic curves using hierarchical regression models.

Evaluation of the risk of radiation exposure from new 18FDG PET/CT plans versus conventional X-ray plans in patients with pediatric cancers.

Objective: Unnecessary radiological examination should be avoided, particularly for children, who are more vulnerable to radiation than adults. Replacement of X-ray examination with 18F-fluoro-2-deoxy-D-glucose (18FDG) positron emission tomography/computed tomography (PET/CT) is a potential option for reduction of radiation exposure, and thus improvement in the quality of life (QOL) of patients. Therefore, this study aimed to evaluate new plans integrating 18FDG PET/CT versus current conventional imaging (CI) plans for patients with pediatric cancers.

Multi-bed-position acquisition technique for deep inspiration breath-hold PET/CT: a preliminary result for pulmonary lesions.

Objective: The deep inspiration breath-hold (DIBH) technique for positron emission tomography/computed tomography (PET/CT) is under investigation for its contribution to the accurate diagnosis of pulmonary lesions. "Step and shoot" or multi-bed-position image acquisition is necessary to improve the accuracy of whole-lung evaluation. The purpose of this study was to describe the method and preliminary results of evaluating pulmonary lesions using multi-bed-position deep inspiration breath-hold (MDIBH) PET/CT.

Evaluation of whole-body cancer screening using 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography: a preliminary report.

Objective: (18)F-2-deoxy-2-fluoro-D-glucose positron emission tomography (FDG-PET) is a promising screening modality targeting whole body. However, the validity of PET cancer screening remains to be assessed. Even the screening accuracy for whole-body screening using FDG-PET has not been evaluated.