[A case of hard metal lung disease in a man who worked as an iron grinder].

The patient was a man who had suffered from repeated pneumothoraces since August 2003, when he was 16 years old. A right pneumothorax was observed at age 21 years, in April 2008. At the same time, a dry cough began to appear and diffuse small nodular shadows in both lung fields were found on a chest X-ray film.

Evaluation of photoinduced changes in stability constants for metal-ion complexes of crowned spirobenzopyran derivatives by electrospray ionization mass spectrometry.

The photoinduced changes of metal-ion complexing ability of crowned spirobenzopyran derivatives were studied by using electrospray ionization mass spectrometry (ESI-MS). Stability constants for the complexation with various metal ions in methanol under visible-irradiation conditions were determined for the first time by ESI-MS. It was found that the stability constants of crowned bis(spirobenzopyran) derivatives with metal ions are decreased dramatically by visible irradiation due to the disappearance of powerful ionic interaction between phenolate anion(s) of the merocyanine form of their spirobenzopyran moiety and a metal ion bound to their crown ether moiety, and the decrease in the stability constants is more pronounced for the multivalent metal-ion complexes.