A Novel Method for the Prediction of the Pedicle Screw Stability: Regional Bone Mineral Density Around the Screw.

Study Design: Prospective feasibility study on consecutive patients.

Objective: The aim of this study was to investigate the ability of regional BMD around the pedicle screw to predict the screw fixation.

Summary Of Background Data: Pedicle screw fixation is the gold standard technique for spinal fusion.

High bone turnover elevates the risk of denosumab-induced hypocalcemia in women with postmenopausal osteoporosis.

Hypocalcemia is the most common major adverse event in patients with osteoporosis receiving the bone resorption inhibitor denosumab; however, limited information is available regarding risk factors of hypocalcemia. Therefore, this study aimed to identify the risk factors of hypocalcemia induced by denosumab treatment for osteoporosis. We retrospectively reviewed the records of patients who had received initial denosumab supplemented with activated vitamin D for osteoporosis.