Publications by authors named "Takeru Nakamura"

Article Synopsis
  • Loeffler's endocarditis is a serious condition marked by eosinophilic infiltration in the heart, leading to complications like embolism and heart failure.
  • A case study focused on a 74-year-old man with an abnormal ECG and a large mass in the heart, diagnosed with Loeffler's endocarditis due to hypereosinophilia.
  • Despite initial anticoagulant treatment, a surgical thrombectomy was performed, leading to the patient's recovery without further issues related to the thrombus or cardiac function deterioration.
View Article and Find Full Text PDF

This paper reports a case in which the patient has survived for 5 years and 6 months after recurrence of colorectal cancer by chemotherapy, and especially in regorafenib as fourth-line therapy has obtained stable disease(SD)for 2 years and 6 months. A man in his 70s underwent left hemicolectomy in the diagnosis of descending colon cancer. Four years and 4 months after the operation, abdominal CT revealed paraaortic lymph node metastasis.

View Article and Find Full Text PDF

The first chemical enantioselective synthesis of N-hydroxyaspartic acid derivatives using chiral multifunctional thiourea/boronic acid organocatalysts was developed. A series of fumaric monoacids underwent an intermolecular asymmetric aza-Michael addition of O-alkyl hydroxylamines in excellent regioselectivity. The addition of another carboxylic acid raised the enantiomeric enrichment up to 97% ee.

View Article and Find Full Text PDF