Publications by authors named "Takehito Sasaki"

Background: Epicardial connections from surrounding structures to the right pulmonary vein (PV) antrum impede PV isolation.

Objective: This study aimed to evaluate the efficacy of an ablation approach targeting epicardial connections for right PV isolation.

Methods: We prospectively enrolled 124 patients with atrial fibrillation undergoing initial PV isolation.

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Background: Periesophageal vagal nerve injury (PNI) is an unpredictable and serious complication of atrial fibrillation (AF) ablation. We aimed to identify the factors associated with symptomatic PNI.

Methods: This study included 1391 patients who underwent ablation index-guided pulmonary vein isolation (PVI) using the CARTO system.

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Article Synopsis
  • - An 81-year-old man with a history of heart surgery and atrial fibrillation was found to have a mass in his right atrium during an echocardiogram, prompting further examination and treatment.
  • - A transesophageal echocardiogram identified a well-defined 23×17 mm tumor located above the cavotricuspid isthmus, leading to careful surgical planning to avoid contact with the heart.
  • - The tumor, attached to the right atrial wall, was successfully removed; pathological analysis revealed myxomatous tissue, and the patient had an uncomplicated recovery, being discharged 23 days post-operation.
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Introduction: Catheter ablation of ectopy originating from the vicinity of the His bundle can be challenging.

Methods And Results: We report a case of a 33-year-old man with narrow QRS ectopy with preferential conduction from a para-Hisian origin to the proximal left fascicles, which was successfully eliminated by radiofrequency ablation in the right coronary cusp, guided by ultrahigh-resolution mapping of the His bundle, bundle branch, and fascicular electrograms.

Conclusion: Some narrow QRS ectopy may originate from the vicinity of the conduction system, instead of the "true" conduction system, and have concealed connections from its origin to the conduction system.

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Introduction: The optimal slow pathway (SP) ablation site in cases with an inferiorly located His bundle (HIS) remains unclear.

Methods And Results: In 45 patients with atrioventricular nodal reentrant tachycardia, the relationship between the HIS location and successful SP ablation site was assessed in electroanatomical maps. We assessed the location of the SP ablation site relative to the bottom of the coronary sinus ostium in the superior-to-inferior (SPSI), anterior-to-posterior (SPAP), and right-to-left (SPRL) directions.

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An 97-year-old woman was diagnosed with complete atrioventricular block and underwent pacemaker implantation( PMI). Three days after the PMI, computed tomography revealed cardiac perforation and migration of the lead to the abdominal cavity. Surgical procedure through median sternotomy was performed, and the penetrated lead was removed.

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Purpose: The left atrial posterior wall (LAPW) can be a target for atrial fibrillation (AF) catheter ablation but is sometimes difficult to completely isolate due to the presence of endocardial-epicardial connections. We aimed to investigate the incidence and distribution of epicardial residual connections (epi-RCs) and the electrogram characteristics at epi-RC sites during an initial LAPW isolation.

Methods: We retrospectively studied 102 AF patients who underwent LAPW mapping before and after a first-pass linear ablation along the superior and inferior LAPW (pre-ablation and post-ablation maps) using an ultra-high-resolution mapping system (Rhythmia, Boston Scientific).

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A 62-year-old man with a history of catheter ablation for atrial fibrillation and atrial tachycardia (AT) received a line of block of the mitral isthmus (MI) and electrical isolation of the left atrial appendage (LAA). Upon entrainment pacing, AT recurred and was diagnosed as peri-mitral AT (PMAT) with electrical irrelevance of MI, LAA, and left pulmonary vein, having a critical isthmus identified as Marshall bundle (MB). MB was then infused with ethanol, leading to the successful treatment of the PMAT.

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We present a case of radiofrequency catheter ablation of persistent atrial fibrillation (AF) with a trigger-based mechanism, guided by novel noncontact charge density mapping, which resulted in the simultaneous achievement of the termination of AF and complete elimination of multiple triggers that induced repeated recurrences of AF immediately after cardioversion. ().

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A 74-year-old man after multiple mitral valve surgeries underwent catheter ablation of a bi-atrial tachycardia (BiAT). Ultra-high resolution activation mapping exhibited a reentrant circuit propagating around the inferior to anterior mitral annulus and right atrial (RA) septum with two interatrial connections. At the transeptal puncture site, continuous fractionated electrograms were recorded during the BiAT, and entrainment pacing revealed a post-pacing interval similar to the tachycardia cycle length, which suggested that the interatrial conduction from the RA to the left atrium (LA) was located just at the transseptal puncture site.

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Unlabelled: A 52-year-old man presented with delta waves on a body surface electrocardiogram, which suggested the presence of a right-sided accessory pathway (AP). Patients with right-sided APs generally have an rS pattern in leads V1-2, while he had an rS in lead V1 but an Rs in lead V2, which could not rule out the possibility of the presence of a septal AP or fasciculoventricular pathway (FVP). On the other hand, patients with septal APs or FVPs generally have a QS pattern in lead V1 instead of an rS pattern.

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Article Synopsis
  • - An 84-year-old man with complete atrioventricular block had a pacemaker implanted, but developed a left pneumothorax two days later, leading to the placement of a chest tube.
  • - A CT scan showed that the right ventricular lead had injured his left lung, prompting a surgical intervention to remove the lead and repair both the right ventricle and left lung.
  • - After recovery, the patient received a new right ventricular lead through intravenous implantation and was discharged 38 days post-surgery.
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The sympathetic nervous system plays an important role in life-threatening ventricular arrhythmias (VAs). Bilateral cardiac sympathetic denervation (BCSD) is performed for refractory VAs. We sought to assess our institutional experience with BCSD in managing treatment-resistant monomorphic ventricular tachycardia (MMVT) in heart failure patients with a reduced ejection fraction (HFrEF).

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  • She was diagnosed with severe aortic stenosis and mild aortic insufficiency, and tests revealed the PVCs were originating from the myocardium under the left coronary cusp.
  • After an aortic valve replacement and cryoablation surgery, her PVCs dropped to 638 beats per day, clinical symptoms resolved, and she was discharged 19 days post-op.
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  • A new ablation catheter (IntellaNav StablePoint) was evaluated for its effectiveness in monitoring contact force (CF) and local impedance (LI) during radiofrequency catheter ablation (RFCA) of the cavotricuspid isthmus (CTI).
  • A retrospective study of 50 patients showed that effective ablation sites had significantly higher initial LI and greater drops in LI compared to ineffective sites, though the initial CF values were similar across both effective and ineffective sites.
  • The study suggests using specific cutoff values of 21 Ω for absolute LI drop and 10.8% for percentage LI drop to improve the prediction of effective ablation outcomes.
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A 77-year-old man underwent radiofrequency catheter ablation of incessant ventricular arrhythmias (VAs) originating from the right ventricular (RV) moderator band (MB). Activation mapping during the VAs exhibited a centrifugal pattern with the earliest activation site (EAS) on the RV septum. A local impedance (LI)-guided radiofrequency application targeting the EAS with a maximum power output of 50W successfully eliminated the VAs and resulted in an LI drop of up to 35 Ω.

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We report a case of an ischemic stroke after a successful catheter ablation of atrial fibrillation (AF) and continuous oral anticoagulation therapy with direct oral anticoagulants (DOACs), which was the trigger for diagnosing antiphospholipid syndrome (APS). A 68-year-old woman underwent catheter ablation of persistent AF and continued oral anticoagulation with edoxaban at a dose of 30 mg once daily after the ablation procedure. An asymptomatic intracerebral hemorrhage was detected by brain computed tomography and magnetic resonance imaging one month post-ablation.

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A 77-year-old man underwent catheter ablation of an atrial tachycardia (AT) after a pulmonary vein (PV) isolation of atrial fibrillation. The AT appeared to be a figure-of-eight reentrant AT by high-resolution mapping: one reentrant circuit rotated clockwise within the right PV (RPV) carina and the other rotated counterclockwise via two conduction gaps along the previous RPV isolation line. However, entrainment pacing from the carina and conduction gaps suggested that the AT was an intra-carina localized reentrant AT with a passive loop around the anterior RPV isolation line via those gaps.

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Purpose: Symptomatic intracerebral hemorrhages (ICHs) are a rare complication after atrial fibrillation (AF) catheter ablation, while the incidence of asymptomatic ICHs detected by magnetic resonance (MR) imaging remains unclear. This study aimed to investigate the incidence, characteristics, and predictors of new-onset ICHs on MR imaging after AF ablation.

Methods: We retrospectively studied 1257 consecutive AF ablation procedures in 1201 patients who underwent MR imaging on the day after the procedure.

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Article Synopsis
  • A 56-year-old woman was diagnosed with an adenosine-sensitive atrial tachycardia (AT) after electrophysiological studies revealed its characteristics, including variability in cycle length and the ability to terminate the tachycardia with adenosine.
  • The tachycardia was mapped using advanced technology, showing that the earliest activation occurred along the lateral mitral annulus, an unusual location for this type of AT typically associated with the right-sided heart structures.
  • A successful radiofrequency catheter ablation was performed at this site, demonstrating that the AT originated from calcium channel-dependent tissue near the mitral annulus rather than the more common AV node or tricuspid annulus area.
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