Publications by authors named "Takehisa Maruyama"
Article Synopsis
- The study investigates the anti-inflammatory effects of magnolol and related compounds on COX-2 expression and NF-κB activation in macrophage-like cells stimulated by Porphyromonas gingivalis fimbriae.
- Various compounds were tested for cytotoxicity, COX-2 mRNA expression, and NF-κB activity, revealing that magnolol and honokiol significantly inhibited COX-2 without being toxic.
- Results showed that only magnolol and honokiol effectively reduced NF-κB activation and COX-2 expression, while other compounds like eugenol and bis-eugenol did not have the same effect.
