Publications by authors named "Takehiko Sho"
Objective: To investigate the value of the ultrasonographically determined size of seminiferous tubules and other conventional parameters for predicting sperm retrieval by microdissection testicular sperm extraction (micro-TESE).
Design: Clinical retrospective study.
Setting: Two urological clinics.
We investigated the clinical effectiveness and safety of tazobactam/piperacillin (TAZ/PIPC) in a 1:8 ratio, a β-lactamase inhibitor with penicillin antibiotic, for the prevention of febrile infectious complication after prostate biopsy. Each patient received a single dose of TAZ/PIPC 4.5 g, 30 min before the biopsy in Group 1 or TAZ/PIPC 4.
View Article and Find Full Text PDFWe retrospectively investigated the incidence of genitourinary tract infection in 5895 patients who underwent transrectal and/or transperineal prostate biopsy procedure between January and December 2011 at 46 institutions belonging to Japanese Research Group for Urinary Tract Infection (JRGU). The total rate of genitourinary tract infection after prostate biopsy was 0.76%, while that following transrectal procedure was 0.
View Article and Find Full Text PDFPurpose: To survey the present condition of administration method of the antimicrobial prophylactic (AMP) agents for the perioperative infection in Japan on revising "The Japanese guidelines for prevention of perioperative infections in urologic field (2006)".
Patients And Methods: With the approval of the Japanese Urological Association (JUA) in 2011, all of the principal urological training institutions certified by JUA (n = 836) were encouraged to participate to survey their adherence to the JUA guidelines (published in 2006) for AMP to prevent perioperative infection in urological field, and 446 (53.3%) institutions responded to the questionnaire.
Article Synopsis
- The Japanese Urological Association introduced the first guidelines for preventing perioperative infections in urological surgeries in 2007, focusing on antimicrobial prophylaxis.
- A study conducted across 10 institutions analyzed data from 513 patients who underwent various urological surgeries to evaluate the effectiveness of these guidelines in practice.
- Results showed that 75.4% of patients received recommended antibiotics, with low rates of surgical site infections (5.9%) and remote infections (4.1%), but further research is needed to fully validate these guidelines.
To propose an appropriate prophylactic antimicrobial therapy for patients undergoing brachytherapy, we evaluated the relationships between various antimicrobial prophylaxis (AMP) protocols and the incidence of postimplant infections in a multicenter cohort study conducted in Japan. The records of 826 patients with localized prostate cancer who underwent a transperineal (125)I brachytherapy procedure between January 2009 and December 2010 were retrospectively reviewed. Perioperative infections, including surgical site and remote infections, were recorded up to postoperative day 30.
View Article and Find Full Text PDFArticle Synopsis
- The study examined high-level carbapenem resistance in Klebsiella pneumoniae strains isolated in Japan, focusing on two strains (Mkp4437 and Mkp4365) from the same patient that showed genetic similarities.
- Both strains carried several resistance genes (including blaIMP-1), but Mkp4437 lacked a protein called OmpK36, which is important for antibiotic uptake.
- The findings suggest that both the production of the IMP-1 enzyme and the absence of OmpK36 contribute to high-level resistance, highlighting the need to monitor OmpK36-deficient strains that could gain further resistance through genetic exchange.
Article Synopsis
- This nationwide study conducted by the Japanese Society of Chemotherapy analyzed 688 bacterial strains isolated from urinary tract infection patients at 28 hospitals in Japan between January and June 2008.
- The most common bacterial strains identified included Escherichia coli (255 strains), Enterococcus faecalis (140 strains), and Pseudomonas aeruginosa (114 strains), among others, with varying levels of antibiotic resistance.
- Key findings revealed that while Enterococcus faecalis strains were mostly susceptible to antibiotics like ampicillin, around 35.7% of E. faecalis showed resistance to fluoroquinolones, and some strains of Pseudomonas aeruginosa were found to be resistant to multiple drug