Effect of particle shape on powder flowability of microcrystalline cellulose as determined using the vibration shear tube method.

Powder flowability of microcrystalline cellulose particles having different particle shapes, whose aspect ratios ranged from 1.8 to 6.4, was measured using the vibration shear tube method.

Measurement of flowability of lubricated powders by the vibrating tube method.

Background: The evaluation of lubricity or flowability of pharmaceutical powders is important for consistent production and quality control of drug products. However, there have been only a few studies on quantitative measurements of the properties of lubricated powders.

Method: Magnesium stearate (MgSt) and sodium stearyl fumarate (SSF) were used as lubricants.