Publications by authors named "Takefumi Otsu"
We investigated the potential efficacy of abaloparatide (Abalo) and zoledronate (ZA) combination therapy for accelerating femoral union in a rat osteotomy model. Nine-week-old male Sprague-Dawley rats were randomly divided into four groups ( = 14 per group): control, abaloparatide (Abalo, 30 μg/kg via subcutaneous injection [s.c.
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- This study explored how combining romosozumab with active vitamin D might speed up fracture healing and improve bone density in ovariectomized rats.
- After creating fracture models in these rats, they were divided into four treatment groups (including control) for 10 weeks before evaluation.
- The results showed that while the combination therapy increased bone mineral density, it did not actually accelerate the healing of fractures.
Artificial cartilages build up a highly lubricious system with the harmony of biomacromolecules and water. Bioconjugate thin films composed of a zwitterionic poly(carboxybetaine methacrylate) (PCB) brush platform and bovine serum albumin (BSA) were designed. BSA conjugation to the PCB brush chains was achieved by carbodiimide chemistry to give PCB brush/BSA conjugate films.
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