Publications by authors named "Takefumi Ishida"
Background: Late-onset circulatory collapse (LCC) is a serious complication in preterm infants and is increasing in Japan. The underlying pathophysiology is thought to be relative adrenal insufficiency and it is more likely to develop at a young gestational age (GA) and in low birthweight (BW) infants. BW to placental weight ratio (BPR) is an index of pregnancy outcomes and early neonatal morbidity.
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- Staphylococcal scalded skin syndrome (SSSS) is linked to toxins produced by Staphylococcus aureus, with a focus on the relationship between anti-ETA antibodies and SSSS in newborns.
- A study involving 106 infants found that preterm infants with SSSS had low levels of anti-ETA antibodies before symptoms appeared, while a full-term infant with the same bacteria was asymptomatic and had high antibody levels.
- The findings suggest that lower levels of anti-ETA antibodies in preterm infants may increase susceptibility to SSSS, especially in those born before 30 weeks gestation.
Nemaline myopathy (NM) is a group of congenital myopathies, characterized by the presence of distinct rod-like inclusions "nemaline bodies" in the sarcoplasm of skeletal muscle fibers. To date, ACTA1, NEB, TPM3, TPM2, TNNT1, and CFL2 have been found to cause NM. We have identified recessive RYR1 mutations in a patient with severe congenital NM, through high-throughput screening of congenital myopathy/muscular dystrophy-related genes using massively parallel sequencing with target gene capture.
View Article and Find Full Text PDFObjective: To investigate postnatal changes in the direction of blood flow through the ductus arteriosus in neonates with meconium-stained amniotic fluid, we measured preductal and postductal oxygen saturation in normal neonates, neonates with meconium-stained amniotic fluid, and a neonate with persistent pulmonary hypertension of the newborn.
Design: Prospective, observational case series report.
Setting: A single, tertiary neonatal intensive care unit.
Objective: To evaluate the impact of suction technique on the rate of meconium removal, oxygenation, and hemodynamics in an animal experimental model of meconium aspiration syndrome (MAS).
Methods: MAS was induced in ventilated rabbits using 3.5 ml/kg of 20% human meconium.