Publications by authors named "Takayoshi Akimoto"

In the present study, we examined the inter-relationships between body water balance, nutritional risk, sarcopenia, and outcome after acute ischemic stroke (AIS) in patients who were living independently. We defined abnormal body water balance as overhydration, with an extracellular fluid/total body water ratio > 0.390.

View Article and Find Full Text PDF

A 58-year-old woman with a history of systemic lupus erythematosus (SLE) who was taking prednisolone and mycophenolate mofetil presented with gait disturbances that progressively worsened over a period of 3 months. Her blood test and cerebrospinal fluid (CSF) examination results did not indicate active SLE. Initial brain magnetic resonance imaging (MRI) revealed a small spotty lesion in the left cerebellar peduncle.

View Article and Find Full Text PDF
Article Synopsis
  • * MRI scans revealed that 14 of the 20 patients with hypoesthesia had brain lesions in the thalamus or pontine tegmentum, while 6 had lesions in other areas.
  • * Patients with hypoesthesia had higher blood pressure and a greater likelihood of small-vessel occlusion, but had shorter hospital stays and similar disability scores compared to those without hypoesthesia.
View Article and Find Full Text PDF

(1) Introduction: Spontaneous spinal epidural hematoma (SSEH) points to hematoma within the epidural space of the spinal cord without traumatic or iatrogenic causes. (2) Case Reports: One patient showed paraplegia, numbness of both legs with acute onset, acute myelopathic signs, subsequent to back pain. Magnetic resonance imaging (MRI) showed hematoma in the posterior part of the thoracic spinal cord.

View Article and Find Full Text PDF

Post-stroke pneumonia (PSP) has an impact on acute ischemic stroke (AIS). Although predictive scores for PSP have been developed, it is occasionally difficult to predict. Clarifying how PSP was treated after its onset in clinical practice is important.

View Article and Find Full Text PDF
Article Synopsis
  • - Acute encephalopathy, a serious brain condition linked to COVID-19, can occur weeks after recovery from the virus, as seen in a case series involving 6 patients aged 65-83 who experienced delayed symptoms.
  • - These patients, who had varying severities of COVID-19 but recovered from lung issues, were hospitalized again due to confusion and neurological deficits like hemiplegia, observed 34 to 67 days post-COVID.
  • - Diagnostic tests revealed elevated CSF protein levels and dysfunction of the blood-brain barrier, but no signs of active infection or neuronal autoantibodies; while some received steroid treatment, it did not improve their encephalopathy symptoms.
View Article and Find Full Text PDF

Rationale: Intramedullary spinal cord abscess (ISCA) is a rare but treatable bacterial infection of the central nervous system, and the etiology in no less than 40% of the cases is cryptogenic. Although a few cases of ISCA in individuals with a right-to-left shunt (RL shunt) have been reported, only few arguments focused on the association between RL shunt and ISCA have been provoked. The right superior vena cava (RSVC) draining into the left atrium (LA) is an uncommon systemic venous anomaly that results in an RL shunt, and this anomaly causes several types of neurological complication such as stroke or brain abscess.

View Article and Find Full Text PDF

Objectives: The anterior choroidal artery (AchA) is one of the collateral vessels in moyamoya disease (MMD). The incidence of cerebral ischemia in MMD was analyzed through the association between development of the AchA and advancement of MMD stage.

Materials And Methods: Twelve patients of MMD with cerebral ischemia (infarction; 9 patients, transient ischemic attack; 3 patients) were enrolled.

View Article and Find Full Text PDF

Background/aims: Undernutrition is common in patients after acute ischemic stroke (AIS) and predicts poor clinical outcomes. We assessed the relationship between undernutrition and prognosis after AIS.

Methods: We retrospectively assessed consecutively hospitalized AIS patients aged ≥65 years.

View Article and Find Full Text PDF

Intramedullary spinal cord abscess (ISCA) is an extremely rare infection of the central nervous system. We report a 17-year old man with ISCA that suggested rupture confirmed by magnetic resonance imaging (MRI). The patient presented with meningeal signs, severe paraplegia, sensory impairment with a sensory level, and urinary retention.

View Article and Find Full Text PDF
Article Synopsis
  • An adult female experienced a condition where she perceived the right eyes of others as enlarged, a phenomenon known as prosopometamorphopsia.
  • Diffusion-weighted imaging revealed an abnormal high-intensity area in her brain, specifically in the splenium of the corpus callosum and the right major forceps.
  • Along with the visual distortion, she also had a left-ear hearing deficit, which is unusual because such a combination hasn't been reported in other patients with similar visual disorders, highlighting the significant role of eye perception in face recognition.
View Article and Find Full Text PDF

Background: A unique patient with MELAS syndrome, who initially masqueraded as having acute encephalitis and was eventually diagnosed with MELAS syndrome harboring a mtDNA 14453G → A mutation, is described.

Case Presentation: A 74-year-old Japanese man was admitted to another hospital due to acute onset of cognitive impairment and psychosis. After 7 days he was transferred to our hospital with seizures and deteriorating psychosis.

View Article and Find Full Text PDF

Background: A concept of sensory tracts in the spinal cord has been established in relation to a dorsolateral pathway which is located in the posterior part of the lateral column and conveys the deep sense.

Methods: The clinical status at onset, neurological symptoms, and magnetic resonance imaging (MRI) findings in 13 patients of spinal cord infarction were studied.

Results: The clinical status was acute in 11 patients and subacute in 2 patients.

View Article and Find Full Text PDF

Background: Infarction of the vermis and the tonsil in the cerebellum presents as truncal and gait ataxia. Acute rotatory vertigo is often present in infarction of the nodulus in the caudal vermis, which is closely associated with the vestibular pathway, but is minor in infarction of the rostral vermis. The rostral vermis receives input from the dorsal spinocerebellar tract (DSCT) which conveys unconsciousness proprioceptive signals from the ipsilateral lower trunk and leg.

View Article and Find Full Text PDF

Objective An abnormal high intensity area (HIA) on diffusion-weighted imaging (DWI) indicates the presence of cytotoxic edema and has been reported to be observed in the hippocampus of patients with transient global amnesia (TGA). The appearance of an HIA on DWI is usually delayed after the onset of patients with amnesia in TGA; thus, the significance of the HIA was evaluated in patients with TGA. Methods Three adult TGA patients who had a unilateral HIA on DWI (right, n=2; left, n=1) were enrolled.

View Article and Find Full Text PDF

Background: Medial medullary infarction (MMI) is a rare ischemic stroke. Frequency of each neurological finding in MMI was different in each study.

Methods: We retrospectively evaluated the medical records of patients with cerebral infarction who were admitted between March 1998 and October 2015.

View Article and Find Full Text PDF

Background: Cardiac myxoma is known to cause repeated events of cerebral embolism. Soft and irregularly shaped myxomas with high mobility are associated with a higher occurrence of cerebral embolism. In contrast, nonmobile cardiac myxomas with a round regular shape are rarely considered to be a cause of cerebral embolism.

View Article and Find Full Text PDF

Background: The prominent features of anterior inferior cerebellar artery (AICA) infarction are vertigo, cerebellar ataxia, and impaired hearing. The present study investigated neurological characteristics associated with AICA infarction.

Materials And Methods: The locations of infarcts in 7 patients (age, 32-72 years) with AICA infarction were divided into the lower lateral pons, the middle cerebellar peduncle (MCP), and the cerebellum.

View Article and Find Full Text PDF

A 43-year-old Japanese man presented with a history of bacterial meningitis (BM). He was admitted to our department with a one-day history of headache and was diagnosed with relapse of BM based on the cerebrospinal fluid findings. The conventional imaging studies showed serial findings suggesting left otitis media, a temporal cephalocele, and meningitis.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the link between executive dysfunction (ED) in Parkinson's disease (PD) and brain connectivity assessed through EEG coherence.
  • The research involved 68 non-demented PD patients who were evaluated with a specific test for executive function and analyzed brain activity in two electrode pairs during different frequency ranges.
  • Results showed that lower EEG coherence on the left side was associated with worse executive function, indicating that decreased connectivity may contribute to executive dysfunction in PD patients.
View Article and Find Full Text PDF
Article Synopsis
  • Postural deformities and executive dysfunction (ED) are common issues in Parkinson's disease (PD), but their relationship isn't well understood.
  • A study with 65 PD patients assessed the severity of postural deformities and executive function using specific rating scales and tests.
  • Results showed a significant correlation between the severity of postural deformities and ED, indicating that more severe deformities are linked to poorer executive function, suggesting a connection to frontal dysfunction in PD patients.
View Article and Find Full Text PDF

A 34-year-old man developed right neck pain. Several hours later, he felt numbness of his extremities and presented at our hospital. He developed right hemiparesis and hypoesthesia of the right extremities.

View Article and Find Full Text PDF