Publications by authors named "Takato Muro"

Article Synopsis
  • * Participants consumed either quercetin-rich or quercetin-free onions, and those in the active group displayed significant improvements in cognitive function and emotional well-being based on various assessments.
  • * The study concluded that quercetin may enhance motivation and reduce depressive symptoms, thereby benefiting cognitive health in older adults.
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Quercetin, which is frequently found in vegetables such as onion, is widely found to have biological activities such as visceral fat reduction. Therefore, we performed this randomised double-blind placebo-controlled parallel-group study and analysed the effects of daily intake of quercetin-rich onion on visceral fat for 12 weeks. Seventy healthy Japanese subjects whose body mass index (BMI) was ≥23 and <30 were recruited and randomly assigned to either the quercetin-rich onion group or placebo group.

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Patients with Alzheimer's disease (AD) experience a wide array of cognitive deficits, which typically include the impairment of explicit memory. In previous studies, the authors reported that a flavonoid, quercetin, reduces the expression of ATF4 and delays memory deterioration in an early-stage AD mouse model. In the present study, the effects of long-term quercetin intake on memory recall were assessed using contextual fear conditioning in aged wild-type mice.

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