Publications by authors named "Takashi Shawn Sato"

Article Synopsis
  • RASopathies are a group of genetic syndromes caused by mutations in genes related to the Ras/MAPK signaling pathway, which affects development and can lead to overlapping features across various disorders like Noonan syndrome and neurofibromatosis type 1.
  • These conditions are rare individually but collectively affect about 1 in 1000 newborns and can lead to a range of issues in the cardiovascular, lymphatic, musculoskeletal, and nervous systems, with both benign and malignant tumors associated with some disorders.
  • Recognizing RASopathies is important for radiologists and healthcare providers, as there are unique imaging characteristics and treatment approaches, including using cancer medications to manage symptoms stemming from the Ras
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Perinatal venous infarcts are underrecognized clinically and at imaging. Neonates may be susceptible to venous infarcts because of hypercoagulable state, compressibility of the dural sinuses and superficial veins due to patent sutures, immature cerebral venous drainage pathways, and drastic physiologic changes of the brain circulation in the perinatal period. About 43% of cases of pediatric cerebral sinovenous thrombosis occur in the neonatal period.

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Objective: H3K27M mutation in gliomas has prognostic implications. Previous magnetic resonance imaging (MRI) studies have reported variable rates of tumoral enhancement, necrotic changes, and peritumoral edema in H3K27M-mutant gliomas, with no distinguishing imaging features compared with wild-type gliomas. We aimed to construct an MRI machine learning (ML)-based radiomic model to predict H3K27M mutation in midline gliomas.

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As the expectations of modern learners change, it is important for educators to adapt. Quick Response codes are an easy way to distribute web-based information to audiences. We familiarize the reader with Quick Response codes and demonstrate a few of the simple ways they can be incorporated into radiology lectures to increase audience engagement including reference dissemination, audience participation, surveys and quizzes.

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ongenital ypotonia, pilepsy, evelopmental delay, and igital nomalies (CHEDDA) is a recently identified neurodevelopmental syndrome which has only 8 reported cases to date since its existence was proposed in 2007. We report a case of CHEDDA syndrome identified in a newborn female with congenital anomalies including Pierre-Robin sequence, arthrogryposis, craniosynostosis, cleft palate, and cardiac abnormalities who subsequently developed epilepsy at 1 month of life. Diagnosis was identified by whole-exome sequencing identifying mutations in a conserved histidine-rich motif within the gene Atrophin-1.

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Chronic recurrent multifocal osteomyelitis (CRMO) is a pediatric autoinflammatory disorder that is characterized by multiple sterile inflammatory bone lesions with a relapsing and remitting course. CRMO belongs to the autoinflammatory family of rheumatologic disorders based on absence of significant titers of autoantibodies and autoreactive T-lymphocytes. In absence of pathognomonic clinical, radiographic or pathological features, diagnosis can be challenging.

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Simulation is a promising method for improving clinician performance, enhancing team training, increasing patient safety, and preventing errors. Training scenarios to enrich medical student and resident education, and apply toward competency assessment, recertification, and credentialing are important applications of simulation in radiology. This review will describe simulation training for procedural skills, interpretive and noninterpretive skills, team-based training and crisis management, professionalism and communication skills, as well as hybrid and in situ applications of simulation training.

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Rationale And Objectives: Chest radiographs can be demanding, making this an area of focus during most first-year resident chest rotations. This often comes at a cost of cross-sectional imaging, and new residents are often not initially comfortable with reading chest computed tomographic angiograms (CTAs) for pulmonary embolisms (PEs). We created a teaching file of CTAs to improve the detection of PEs.

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