Genome-wide association study of sensory disturbances in the inferior alveolar nerve after bilateral sagittal split ramus osteotomy.

Background: Bilateral sagittal split ramus osteotomy (BSSRO) is a common orthognatic surgical procedure. Sensory disturbances in the inferior alveolar nerve, including hypoesthesia and dysesthesia, are frequently observed after BSSRO, even without distinct nerve injury. The mechanisms that underlie individual differences in the vulnerability to sensory disturbances have not yet been elucidated.

Intravenous sedation and hemodynamic changes during dental implant surgery.

Purpose: The purpose of the present study was to determine whether intravenous sedation during dental implant surgery contributed to stabilization of hemodynamics.

Materials And Methods: Two hundred fifty-five consecutive patients treated with dental implants were randomly assigned to receive either intravenous sedation with local anesthesia (sedation group, n = 123) or local anesthesia only (nonsedation group, n = 132). Midazolam and propofol were used synergistically as sedative agents.

Automatic segmentation of teeth from dentomaxillofacial 3D-CT images.

CT is an effective tool for image diagnosis because it enables noninvasive observation of internal organs. In the course of CT, 3D-CT, such as a helical scanning CT and a multi-detector row CT, has been developed. With the use of 3D-CT, organs can be observed from several viewing directions.

Antimicrobial activity of super-oxidised water against oral microorganisms.

Objective: The radical anion of oxygen (O(-)) is extremely oxidative and shows high reactivity. In this study, the antibacterial activity of water super-oxidised water containing high concentration of O(-) (O(-)-water) was tested against cultured planktonic cells of cariogenic bacteria, periodontopathic bacteria and Candida albicans.

Methods: O(-)-water was prepared using the AOE-750 (Oxy Japan Corporation, Japan) and its antibacterial activity against pure culture of Streptococcus sobrinus, Porphyromonas gingivalis, Prevotella intermedia, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum and C.

Systemic Inflammatory Response Syndrome and postoperative complications after orthognathic surgery.

Symptoms of Systemic Inflammatory Response Syndrome (SIRS) presenting immediately after surgery have lately been regarded as potential warnings of impending postoperative complications and multiple organ failure. Reports discussing the relationship between operative stress and SIRS are found in the field of digestive surgery, but not in that of oral surgery. Sixty-five patients with jaw deformity who had undergone maxillary and mandibular orthognathic surgery (Le Fort I osteotomy and sagittal splitting ramus osteotomy) between September 2003 and October 2006 were involved in this study.

Patient in whom surgery was selected to improve mandible position after changing doctors.

A patient who visited our department after job relocation was reexamined, and a marked discrepancy was found in mandibular position between centric occlusion and centric relation. Although the patient was originally scheduled to undergo orthodontic treatment only, the results of comprehensive tests indicated that surgery would be needed to resolve this discrepancy. Surgery was performed with the patient's consent, yielding favorable results.

Dental implant treatment with different techniques for sinus floor elevation--a case report.

A 60-year-old man with missing maxillary molar teeth received dental implant therapy for reconstruction of occlusion. Sinus floor elevation with autogenous bone graft consisting of iliac bone block and particulate cancellous bone and marrow (PCBM) was performed in the bilateral maxillary sinuses for implant placement. On the right side, bone height in the molar region was less than 2mm.

Adenomatoid odontogenic tumor arising from the mandibular molar region: a case report and review of the literature.

This case report describes a rare case of an adenomatoid odontogenic tumor (AOT) arising in the mandibular third molar region of a 20-year-old female. The tumor was a well-circumscribed intraosseous lesion with an embedded tooth. Histologically, the induction of extensive globular calcification was evident in addition to the characteristic histological features of AOT.

Oral cancer research with an emphasis on genomic analysis.

Ablative surgery has been a standard procedure for many years, but during the past few years there has been a significant improvement in our understanding of invasion and metastasis in oral cancer. Each procedure has to be planned individually. Before surgery, every attempt must have been made to arrive at a proper diagnosis, including the exact nature and aggressiveness of the tumor and an analysis of the patient's genetic background.