Publications by authors named "Takashi Fumita"
Purpose: The study compares the surgical outcomes of very-early-onset ulcerative colitis (VEO-UC), which is a rare disease diagnosed in pediatric patients < 6 years, with those of older pediatric patients with ulcerative colitis (UC).
Methods: A retrospective observational study of 57 pediatric patients with UC was conducted at a single center. The study compared surgical complications and postoperative growth between the two groups.
Purpose: This study evaluated the abdominal aortic diameter in high-risk neuroblastoma (NB) patients and the risk of aortic narrowing following intensive treatment.
Methods: We measured the aortic diameter at four specific levels of the abdominal aorta (diaphragmatic crus, celiac axis, and the root of the superior (SMA) and inferior (IMA) mesenteric arteries) on contrast CT scans. The control group consisted of 56 children with non-oncologic disorders, while the NB group included 35 patients with high-risk abdominal NB.
Article Synopsis
- The study investigates the presence and function of regulatory T-cells (Tregs) in liver tissues of patients with biliary atresia (BA), a condition linked to immunological issues.
- Researchers found that BA patients had higher numbers of lymphocytes, CD4 cells, and Tregs in their liver compared to control patients, although the ratio of Tregs among CD4 cells was similar in both groups.
- Despite the increased presence of Tregs, they did not effectively suppress inflammation in BA patients, indicating a need for further study on Treg functionality in this context.
Article Synopsis
- - The study investigated circulating regulatory T-cells (Tregs) in biliary atresia (BA) patients to understand their frequency and function compared to healthy controls.
- - Researchers analyzed blood samples from 25 BA patients and 24 controls, finding no significant differences in Treg frequency or function between the two groups.
- - The results suggest that circulating Tregs might not play a significant role in the development of BA, prompting further research into Treg profiles in the affected liver and local tissues.